HsaEX6047450 @ hg38
Exon Skipping
Gene
ENSG00000137225 | CAPN11
Description
calpain 11 [Source:HGNC Symbol;Acc:HGNC:1478]
Coordinates
chr6:44176581-44177420:+
Coord C1 exon
chr6:44176581-44176655
Coord A exon
chr6:44176838-44176998
Coord C2 exon
chr6:44177242-44177420
Length
161 bp
Sequences
Splice sites
3' ss Seq
CCACCCCCACCCCACCACAGGAT
3' ss Score
6.7
5' ss Seq
CTGGTGGGT
5' ss Score
6.29
Exon sequences
Seq C1 exon
TGCCAGGGAGTGGGAAGAGGTGGCCTCAGACATCCAGATGCAGCTGCTGCACAAGACGGAGGACGGGGAGTTCTG
Seq A exon
GATGTCCTACCAAGATTTCCTGAACAACTTCACGCTCCTGGAGATCTGCAACCTCACGCCTGATACACTCTCTGGGGACTACAAGAGCTACTGGCACACCACCTTCTACGAGGGCAGCTGGCGCAGAGGCAGCTCCGCAGGGGGCTGCAGGAACCACCCTG
Seq C2 exon
GCACGTTCTGGACCAACCCCCAGTTTAAGATCTCTCTTCCTGAGGGGGATGACCCAGAGGATGACGCAGAGGGCAATGTTGTGGTCTGCACCTGCCTGGTGGCCCTAATGCAGAAGAACTGGCGGCATGCACGGCAGCAGGGAGCCCAGCTGCAGACCATTGGCTTTGTCCTCTACGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137225-'16-18,'16-17,17-18
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.018 C2=0.089
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=FE(8.3=100)
A:
PF0064816=Peptidase_C2=PD(6.3=34.5),PF0106717=Calpain_III=PU(15.1=43.6)
C2:
PF0106717=Calpain_III=FE(37.1=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGGAGTGGGAAGAGGTGG
R:
CGCGTAGAGGACAAAGCCAAT
Band lengths:
251-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains