HsaEX6057508 @ hg38
Exon Skipping
Gene
ENSG00000144821 | MYH15
Description
myosin heavy chain 15 [Source:HGNC Symbol;Acc:HGNC:31073]
Coordinates
chr3:108405338-108414428:-
Coord C1 exon
chr3:108414232-108414428
Coord A exon
chr3:108408280-108408404
Coord C2 exon
chr3:108405338-108405453
Length
125 bp
Sequences
Splice sites
3' ss Seq
TTTCTTACCTCTGTCTCCAGAAG
3' ss Score
9.17
5' ss Seq
GAGGTATTA
5' ss Score
6.46
Exon sequences
Seq C1 exon
TCCCAGAGTGCCCTGGCCCATGCCCTGCAGAAGGCTCAGCGTGACTGTGACCTTCTACGAGAGCAGTATGAGGAAGAACAAGAGGTCAAGGCTGAGCTGCACCGGACCTTATCCAAAGTCAATGCTGAAATGGTGCAATGGAGAATGAAGTATGAAAACAATGTCATCCAGAGAACAGAAGACTTGGAGGATGCCAA
Seq A exon
AAGAGATTTCTAATCTGACAAACCAGGTTAGAGAAGGGACCAAGAACTTAACTGAAATGGAAAAGGTCAAGAAACTAATTGAAGAAGAGAAGACAGAAGTCCAGGTGACACTGGAAGAAACAGAG
Seq C2 exon
GGAGCCCTGGAACGTAATGAAAGCAAGATTCTTCATTTCCAGCTTGAACTCTTGGAAGCTAAAGCAGAACTTGAAAGAAAGCTTTCAGAGAAAGATGAAGAAATAGAAAATTTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144821_MULTIEX1-3/4=C1-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.124 A=0.542 C2=0.120
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(12.4=100)
A:
PF0157614=Myosin_tail_1=FE(4.8=100)
C2:
PF0157614=Myosin_tail_1=FE(4.4=100)
Main Skipping Isoform:
ENST00000273353fB20490
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCATGCCCTGCAGAAG
R:
AGCTTCCAAGAGTTCAAGCTGG
Band lengths:
242-367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains