HsaEX6062952 @ hg38
Exon Skipping
Gene
ENSG00000119408 | NEK6
Description
NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749]
Coordinates
chr9:124339571-124353307:+
Coord C1 exon
chr9:124339571-124339665
Coord A exon
chr9:124347709-124347822
Coord C2 exon
chr9:124350837-124353307
Length
114 bp
Sequences
Splice sites
3' ss Seq
GTTGTTCCCGTCCCTTGCAGATG
3' ss Score
11.8
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
TGGGGACGCCCTACTACATGTCACCGGAGAGGATCCATGAGAACGGCTACAACTTCAAGTCCGACATCTGGTCCCTGGGCTGTCTGCTGTACGAG
Seq A exon
ATGGCAGCCCTCCAGAGCCCCTTCTATGGAGATAAGATGAATCTCTTCTCCCTGTGCCAGAAGATCGAGCAGTGTGACTACCCCCCACTCCCCGGGGAGCACTACTCCGAGAAG
Seq C2 exon
TTACGAGAACTGGTCAGCATGTGCATCTGCCCTGACCCCCACCAGAGACCTGACATCGGATACGTGCACCAGGTGGCCAAGCAGATGCACATCTGGATGTCCAGCACCTGAGCGTGGATGCACCGTGCCTTATCAAAGCCAGCACCACTTTGCCTTACTTGAGTCGTCTTCTCTTCGAGTGGCCACCTGGTAGCCTAGAACAGCTAAGACCACAGGGTTCAGCAGGTTCCCCAAAAGGCTGCCCAGCCTTACAGCAGATGCTGAAGGCAGAGCAGCTGAGGGAGGGGCGCTGGCCACATGTCACTGATGGTCAGATTCCAAAGTCCTTTCTTTATACTGTTGTGGACAATCTCAGCTGGGTCAATAAGGGCAGGTGGTTCAGCGAGCCACGGCAGCCCCCTGTATCTGGATTGTAATGTGAATCTTTAGGGTAATTCCTCCAGTGACCTGTCAAGGCTTATGCTAACAGGAGACTTGCAGGAGACCGTGTGATTTGTGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119408-'31-44,'31-40,36-44=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(11.8=100)
A:
PF0006920=Pkinase=FE(14.1=100)
C2:
PF0006920=Pkinase=PD(10.7=75.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTACTACATGTCACCGGA
R:
AGTAAGGCAAAGTGGTGCTGG
Band lengths:
247-361
Functional annotations
There are 1 annotated functions for this event
PMID: 16476580
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, pull down. ELM ID: ELMI002028; ELM sequence: ALQSPF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains