MmuEX0031462 @ mm10
Exon Skipping
Gene
ENSMUSG00000026749 | Nek6
Description
NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638]
Coordinates
chr2:38577239-38594606:+
Coord C1 exon
chr2:38577239-38577333
Coord A exon
chr2:38582383-38582496
Coord C2 exon
chr2:38585280-38594606
Length
114 bp
Sequences
Splice sites
3' ss Seq
TTTGTATTCCTTCATTGTAGATG
3' ss Score
9.11
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
TGGGAACACCATACTACATGTCACCCGAGAGAATCCATGAGAATGGCTACAACTTCAAGTCAGACATCTGGTCCCTAGGCTGCCTGCTGTATGAG
Seq A exon
ATGGCAGCTCTCCAGAGCCCCTTCTATGGAGATAAGATGAATCTCTTCTCCCTCTGCCAAAAGATTGAGCAGTGTGACTACCCGCCTCTCCCGGGAGAGCACTACTCTGAGAAG
Seq C2 exon
CTTCGGGAACTGGTCAGTATGTGTATCTACCCTGACCCTGACCACCGACCTGACATTGTATATGTGCACCAGGTGGCTAGACAGATGCACGTCTGGACATCCAGCACCTGAACGCAACACACCTCATCAAAGCCAAGTCACTTGTCTTACTTGAGTCCTCTCCCCAAGTGGTACCTGGAAGCCCCCACAGCCAAGACTAGAGGACTCTCAGCTGGCTCCACCCAGCGGAAAACAGCTGGGCTATGGTCAGACTCCAAAGTCCTTTCTTTGAACTGTCGCAGACAATCTGAGCTGGGATGAGTGGGGAGGGGTTTGGCAGCCATGGAAACCCCTTGTACCTACTGAAATGTGAACCTCTGCCTGGTTGCTTCAGACCCGTCCAGGCCCACACGGTCAGGAGACTTGAAGGGAGCTGGGTGACTAGTGTGGGCCAGCCTTTGCAAATGGTTACCACCATTGGTTTAGTTCTTAGTACCTTTCCATACAATCAGGCTGTGTGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026749_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(11.9=100)
A:
PF0006920=Pkinase=FE(14.2=100)
C2:
PF0006920=Pkinase=PD(10.0=70.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCACCCGAGAGAATCCATGA
R:
CCACTTGGGGAGAGGACTCAA
Band lengths:
248-362
Functional annotations
There are 1 annotated functions for this event
PMID: 16476580
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, pull down. ELM ID: ELMI002028; ELM sequence: ALQSPF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types