DreEX0050177 @ danRer10
Exon Skipping
Gene
ENSDARG00000037963 | nek6
Description
NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133]
Coordinates
chr21:8265063-8268605:-
Coord C1 exon
chr21:8268511-8268605
Coord A exon
chr21:8267631-8267744
Coord C2 exon
chr21:8265063-8265185
Length
114 bp
Sequences
Splice sites
3' ss Seq
GTGATATTTGTGTCTCTCAGATG
3' ss Score
9.11
5' ss Seq
AAGGTACAA
5' ss Score
6.82
Exon sequences
Seq C1 exon
TTGGAACTCCATATTACATGTCTCCAGAGAGGATTCATGAAAACGGCTACAACTTCAAATCAGACATCTGGTCTCTGGGCTGCTTACTGTATGAG
Seq A exon
ATGGCAGCTCTGCACAGCCCCTTTTACAGTGACAAGATGAACCTGCTCTCGCTGTGCCATAAGATTGAACAGTGTGAATACCCACCTCTGCCAACAGAGCACTACTCACAGAAG
Seq C2 exon
TTTAGAGATCTGGTCAGTATGTGCATCAACCCAGAGCCCGACCAGCGGCCCGACATCAGCTTCGTCCTGCAGTTTTCCACACAGATGAAGCTGTGGACGACCAGCACCTGATGCAAACACTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000037963_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(11.9=100)
A:
PF0006920=Pkinase=FE(14.2=100)
C2:
PF0006920=Pkinase=PD(10.4=71.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAACTCCATATTACATGTCTCCA
R:
ATCAGGTGCTGGTCGTCCA
Band lengths:
206-320
Functional annotations
There are 1 annotated functions for this event
PMID: 16476580
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, pull down. ELM ID: ELMI002028; ELM sequence: ALQSPF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]