HsaEX6065064 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9104239-9106605:-
Coord C1 exon
chr12:9106491-9106605
Coord A exon
chr12:9106236-9106345
Coord C2 exon
chr12:9104239-9104400
Length
110 bp
Sequences
Splice sites
3' ss Seq
ATTTTTTTCTCTTTTTTCAGTGG
3' ss Score
10.42
5' ss Seq
CAGGTGGAG
5' ss Score
2.57
Exon sequences
Seq C1 exon
CTAAACAGCCATGGCTGCTTCTATCAGCAAGTAAAAACCAAGGTCTTCCAGCTGAAGAGGAAGGAGTATGAAATGAAACTTCACACTGAGGCCCAGATCCAAGAAGAAGGAACAG
Seq A exon
TGGTGGAATTGACTGGAAGGCAGTCCAGTGAAATCACAAGAACCATAACCAAACTCTCATTTGTGAAAGTGGACTCACACTTTCGACAGGGAATTCCCTTCTTTGGGCAG
Seq C2 exon
GTGCGCCTAGTAGATGGGAAAGGCGTCCCTATACCAAATAAAGTCATATTCATCAGAGGAAATGAAGCAAACTATTACTCCAATGCTACCACGGATGAGCATGGCCTTGTACAGTTCTCTATCAACACCACCAATGTTATGGGTACCTCTCTTACTGTTAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899-'27-24,'27-18,30-24=AN
Average complexity
A_S
Mappability confidence:
92%=100=86%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.051 A=0.027 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCATGGCTGCTTCTATCAG
R:
GGTACCCATAACATTGGTGGTGT
Band lengths:
255-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains