HsaEX6065069 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9095539-9099523:-
Coord C1 exon
chr12:9099381-9099523
Coord A exon
chr12:9098607-9098756
Coord C2 exon
chr12:9095539-9095700
Length
150 bp
Sequences
Splice sites
3' ss Seq
CTTTTGTTCCAATTTCACAGGTG
3' ss Score
10.35
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
Exon sequences
Seq C1 exon
TGAAGGGCCATTTTTCCATCTCAATCCCTGTGAAGTCAGACATTGCTCCTGTCGCTCGGTTGCTCATCTATGCTGTTTTACCTACCGGGGACGTGATTGGGGATTCTGCAAAATATGATGTTGAAAATTGTCTGGCCAACAAG
Seq A exon
GTGGATTTGAGCTTCAGCCCATCACAAAGTCTCCCAGCCTCACACGCCCACCTGCGAGTCACAGCGGCTCCTCAGTCCGTCTGCGCCCTCCGTGCTGTGGACCAAAGCGTGCTGCTCATGAAGCCTGATGCTGAGCTCTCGGCGTCCTCG
Seq C2 exon
GTTTACAACCTGCTACCAGAAAAGGACCTCACTGGCTTCCCTGGGCCTTTGAATGACCAGGACAATGAAGACTGCATCAATCGTCATAATGTCTATATTAATGGAATCACATATACTCCAGTATCAAGTACAAATGAAAAGGATATGTACAGCTTCCTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899_MULTIEX1-3/17=2-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.020 C2=0.144
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=FE(31.5=100)
A:
PF077039=A2M_N_2=PD(26.2=78.0)
C2:
PF077039=A2M_N_2=PD(21.7=83.3)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCGGTTGCTCATCTATGCT
R:
AGGAAGCTGTACATATCCTTTTCA
Band lengths:
248-398
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains