HsaEX6066557 @ hg19
Exon Skipping
Gene
ENSG00000139610 | CELA1
Description
chymotrypsin-like elastase family, member 1 [Source:HGNC Symbol;Acc:3308]
Coordinates
chr12:51733644-51736484:-
Coord C1 exon
chr12:51736359-51736484
Coord A exon
chr12:51735028-51735164
Coord C2 exon
chr12:51733644-51733789
Length
137 bp
Sequences
Splice sites
3' ss Seq
AGTCTCCTTTTCTCCTGCAGCTA
3' ss Score
10.3
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
Exon sequences
Seq C1 exon
CCAGAAGACTTTCCGCGTGGTGGCTGGAGACCATAACCTGAGCCAGAATGATGGCACTGAGCAGTACGTGAGTGTGCAGAAGATCGTGGTGCATCCATACTGGAACAGCGATAACGTGGCTGCCGG
Seq A exon
CTATGACATCGCCCTGCTGCGCCTGGCCCAGAGCGTTACCCTCAATAGCTATGTCCAGCTGGGTGTTCTGCCCCAGGAGGGAGCCATCCTGGCTAACAACAGTCCCTGCTACATCACAGGCTGGGGCAAGACCAAGA
Seq C2 exon
CCAATGGGCAGCTGGCCCAGACCCTGCAGCAGGCTTACCTGCCCTCTGTGGACTACGCCATCTGCTCCAGCTCCTCCTACTGGGGCTCCACTGTGAAGAACACCATGGTGTGTGCTGGTGGAGATGGAGTTCGCTCTGGATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139610-'3-4,'3-3,4-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(18.0=100)
A:
PF0008921=Trypsin=FE(19.7=100)
C2:
PF0008921=Trypsin=FE(20.6=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGTGGCTGGAGACCATAAC
R:
GCATCCAGAGCGAACTCCATC
Band lengths:
253-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)