HsaEX6069269 @ hg19
Exon Skipping
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 (GAP1 like) [Source:HGNC Symbol;Acc:9873]
Coordinates
chr12:113552605-113553593:-
Coord C1 exon
chr12:113553440-113553593
Coord A exon
chr12:113553005-113553069
Coord C2 exon
chr12:113552605-113552717
Length
65 bp
Sequences
Splice sites
3' ss Seq
ACTTCCTCCTGTCCTCCCAGTGG
3' ss Score
9.48
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GAGGACACTGCTAGCCCCTTGGCTTTGCTGGAAGAGCTGACCTTGGGGGACTGCCGCCAGGACCTTGCCACCAAGCTGGTGAAACTCTTTCTTGGCCGGGGACTGGCTGGGCGCTTTCTGGACTATCTCACCCGGCGTGAGGTGGCTCGGACCA
Seq A exon
TGGACCCCAACACCCTCTTCCGTTCTAACTCCCTGGCATCCAAGTCGATGGAACAGTTTATGAAG
Seq C2 exon
CTCGTGGGCATGCCCTACCTGCACGAGGTCCTGAAGCCTGTGATTAGCCGTGTCTTTGAGGAGAAGAAGTACATGGAGCTGGATCCCTGCAAGATGGACCTGGGCCGCACCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344-'10-12,'10-11,11-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.019 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0061614=RasGAP=PU(6.8=25.0)
A:
PF0061614=RasGAP=FE(11.1=100)
C2:
PF0061614=RasGAP=FE(19.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAACTCTTTCTTGGCCGGG
R:
CATCTTGCAGGGATCCAGCTC
Band lengths:
171-236
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)