HsaEX6075434 @ hg19
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66214676-66220865:-
Coord C1 exon
chr15:66220763-66220865
Coord A exon
chr15:66215161-66215307
Coord C2 exon
chr15:66214676-66214810
Length
147 bp
Sequences
Splice sites
3' ss Seq
AGTCTGCCTCTGGCCCACAGGCA
3' ss Score
7.69
5' ss Seq
GAAGTAAGG
5' ss Score
6.38
Exon sequences
Seq C1 exon
GATGGCACATTTGGGCTGAACTGCAGTGAACACTGTGACTGCAGCCATGCTGATGGATGTGACCCCGTCACAGGCCACTGCTGCTGCCTGGCCGGATGGACAG
Seq A exon
GCATCCGCTGTGACAGCACGTGTCCACCTGGCCGCTGGGGCCCCAACTGCTCTGTCTCCTGCAGCTGTGAGAATGGAGGCTCCTGCTCCCCAGAGGATGGGAGCTGCGAGTGTGCCCCTGGCTTCCGAGGACCCTTATGCCAGAGAA
Seq C2 exon
TCTGCCCCCCTGGGTTCTATGGCCACGGCTGCGCCCAGCCATGCCCCCTCTGCGTGCACAGCAGCAGGCCCTGCCACCACATCAGCGGCATCTGTGAGTGCCTCCCAGGATTCTCTGGAGCTCTCTGCAACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'19-20,'19-19,20-20=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005319=Laminin_EGF=PU(68.8=66.0)
C2:
PF0005319=Laminin_EGF=PD(29.2=30.4),PF126612=hEGF=WD(100=28.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCACATTTGGGCTGAACTG
R:
CTTGGTTGCAGAGAGCTCCAG
Band lengths:
236-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)