HsaEX6076687 @ hg19
Exon Skipping
Gene
ENSG00000154227 | LASS3
Description
ceramide synthase 3 [Source:HGNC Symbol;Acc:23752]
Coordinates
chr15:101019633-101024873:-
Coord C1 exon
chr15:101024755-101024873
Coord A exon
chr15:101020194-101020251
Coord C2 exon
chr15:101019633-101019683
Length
58 bp
Sequences
Splice sites
3' ss Seq
ATTTTTCTTTCTTTTGGCAGCTG
3' ss Score
9.51
5' ss Seq
GATGTAAGT
5' ss Score
9.11
Exon sequences
Seq C1 exon
ACTGATATTTATGGACTGGCAAAGAAGTGTAACTTGACGGAGCGCCAGGTGGAAAGATGGTTTAGGAGTCGGCGGAATCAAGAGAGGCCTTCCAGGCTGAAGAAATTCCAGGAAGCTTG
Seq A exon
CTGGAGATTTGCATTTTACTTAATGATCACTGTTGCTGGAATTGCGTTTCTTTATGAT
Seq C2 exon
AAACCTTGGCTATATGACTTATGGGAGGTTTGGAATGGCTATCCCAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000154227-'7-8,'7-7,8-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PD(50.9=72.5),PF0379811=TRAM_LAG1_CLN8=PU(16.1=12.5)
A:
PF0379811=TRAM_LAG1_CLN8=FE(61.3=100)
C2:
PF0379811=TRAM_LAG1_CLN8=FE(8.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTGTAACTTGACGGAGCGC
R:
GGATAGCCATTCCAAACCTCCC
Band lengths:
139-197
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)