HsaEX6080569 @ hg38
Exon Skipping
Gene
ENSG00000104368 | PLAT
Description
plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051]
Coordinates
chr8:42180242-42182022:-
Coord C1 exon
chr8:42181937-42182022
Coord A exon
chr8:42180490-42180685
Coord C2 exon
chr8:42180242-42180378
Length
196 bp
Sequences
Splice sites
3' ss Seq
CCTCGTCCTTTCCTCCCCAGCCA
3' ss Score
9.62
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
Exon sequences
Seq C1 exon
GAATCCTGATGGGGATGCCAAGCCCTGGTGCCACGTGCTGAAGAACCGCAGGCTGACGTGGGAGTACTGTGATGTGCCCTCCTGCT
Seq A exon
CCACCTGCGGCCTGAGACAGTACAGCCAGCCTCAGTTTCGCATCAAAGGAGGGCTCTTCGCCGACATCGCCTCCCACCCCTGGCAGGCTGCCATCTTTGCCAAGCACAGGAGGTCGCCCGGAGAGCGGTTCCTGTGCGGGGGCATACTCATCAGCTCCTGCTGGATTCTCTCTGCCGCCCACTGCTTCCAGGAGAG
Seq C2 exon
GTTTCCGCCCCACCACCTGACGGTGATCTTGGGCAGAACATACCGGGTGGTCCCTGGCGAGGAGGAGCAGAAATTTGAAGTCGAAAAATACATTGTCCATAAGGAATTCGATGATGACACTTACGACAATGACATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000104368-'18-22,'18-21,20-22=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PD(34.1=93.3)
A:
PF0008921=Trypsin=PU(20.7=77.3)
C2:
PF0008921=Trypsin=FE(18.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAATCCTGATGGGGATGCCAA
R:
TCATTGTCGTAAGTGTCATCATCGA
Band lengths:
218-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains