HsaEX6083085 @ hg19
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B, cGMP-specific, rod, beta [Source:HGNC Symbol;Acc:8786]
Coordinates
chr4:655923-656976:+
Coord C1 exon
chr4:655923-656030
Coord A exon
chr4:656298-656407
Coord C2 exon
chr4:656889-656976
Length
110 bp
Sequences
Splice sites
3' ss Seq
AGGTGGCCCTGTCTCTACAGACC
3' ss Score
8.24
5' ss Seq
GAAGTAGGC
5' ss Score
3.93
Exon sequences
Seq C1 exon
GTCCTGGTGCGGTTCCTGTTCTCCATCAGCAAAGGGTACCGGAGAATCACCTACCACAACTGGCGCCACGGCTTCAACGTGGCCCAGACGATGTTCACGCTGCTCATG
Seq A exon
ACCGGCAAACTGAAGAGCTACTACACGGACCTGGAGGCCTTCGCCATGGTGACAGCCGGCCTGTGCCATGACATCGACCACCGCGGCACCAACAACCTGTACCAGATGAA
Seq C2 exon
GTCCCAGAACCCCTTGGCTAAGCTCCACGGCTCCTCGATTTTGGAGCGGCACCACCTGGAGTTTGGGAAGTTCCTGCTCTCGGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256-'23-21,'23-20,24-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(7.2=50.0)
A:
PF0023314=PDEase_I=FE(14.5=100),PF0771711=OB_NTP_bind=PU(18.6=70.3)
C2:
PF0023314=PDEase_I=FE(11.6=100),PF0771711=OB_NTP_bind=FE(20.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGGTGCGGTTCCTGTTC
R:
CTCCTCCGAGAGCAGGAACTT
Band lengths:
194-304
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)