HsaEX6084609 @ hg38
Exon Skipping
Gene
ENSG00000185873 | TMPRSS11B
Description
transmembrane protease, serine 11B [Source:HGNC Symbol;Acc:HGNC:25398]
Coordinates
chr4:68229257-68232416:-
Coord C1 exon
chr4:68232378-68232416
Coord A exon
chr4:68231203-68231380
Coord C2 exon
chr4:68229257-68229516
Length
178 bp
Sequences
Splice sites
3' ss Seq
TAAATAAATCCTTTCTCTAGGTT
3' ss Score
8.7
5' ss Seq
TAAGTAAGT
5' ss Score
8.07
Exon sequences
Seq C1 exon
AAATCAGCAAGGCTGCTTCTGAAATGCTTACCAACAACT
Seq A exon
GTTGTGGGAGACAAGTAGCCAACAGTATCATAACTGGCAACAAAATTGTGAATGGAAAAAGCTCCCTGGAGGGGGCATGGCCATGGCAGGCCAGCATGCAATGGAAAGGCCGTCACTACTGTGGAGCCTCTCTGATCAGCAGCAGGTGGCTATTATCTGCAGCTCACTGCTTTGCTAA
Seq C2 exon
GAAAAATAATTCAAAAGATTGGACTGTCAACTTTGGAATTGTAGTAAATAAACCATATATGACACGGAAAGTCCAAAACATTATTTTTCATGAAAATTATAGCAGTCCTGGGCTTCATGATGATATTGCCCTTGTGCAGCTTGCTGAAGAAGTTTCTTTTACAGAGTACATTCGTAAGATTTGTCTTCCTGAAGCCAAAATGAAGCTCTCAGAAAATGACAATGTTGTAGTTACAGGTTGGGGAACACTTTATATGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185873-'6-7,'6-5,8-7=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0008921=Trypsin=PU(19.5=73.3)
C2:
PF0008921=Trypsin=FE(38.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAGGCTGCTTCTGAAATGC
R:
AGAGCTTCATTTTGGCTTCAGGA
Band lengths:
242-420
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains