HsaEX6087211 @ hg38
Exon Skipping
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186280223-186284260:+
Coord C1 exon
chr4:186280223-186280385
Coord A exon
chr4:186280474-186280580
Coord C2 exon
chr4:186284092-186284260
Length
107 bp
Sequences
Splice sites
3' ss Seq
CGTTTTGTTTCCAACTGCAGGGG
3' ss Score
9.37
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
TGTTCTGCCATTCTTCATTTTACCATGACACTGATTTCTTGGGAGAAGAACTGGATATTGTTGCTGCAAAAAGTCACGAGGCCTGCCAGAAACTGTGCACCAATGCCGTCCGCTGCCAGTTTTTTACCTATACCCCAGCCCAAGCATCCTGCAACGAAGGGAA
Seq A exon
GGGCAAGTGTTACTTAAAGCTTTCTTCAAACGGATCTCCAACTAAAATACTTCACGGGAGAGGAGGCATCTCTGGATACACATTAAGGTTGTGTAAAATGGATAATG
Seq C2 exon
AGTGTACCACCAAAATCAAGCCCAGGATCGTTGGAGGAACTGCGTCTGTTCGTGGTGAGTGGCCGTGGCAGGTGACCCTGCACACAACCTCACCCACTCAGAGACACCTGTGTGGAGGCTCCATCATTGGAAACCAGTGGATATTAACAGCCGCTCACTGTTTCTATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926-'15-21,'15-15,16-21=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF142951=PAN_4=PU(86.3=80.0)
A:
PF142951=PAN_4=PD(11.8=16.2)
C2:
PF0008921=Trypsin=PU(20.3=82.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCAGAAACTGTGCACCAAT
R:
CCATAGAAACAGTGAGCGGCT
Band lengths:
249-356
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains