HsaEX6091357 @ hg38
Exon Skipping
Gene
ENSG00000197540 | GZMM
Description
granzyme M [Source:HGNC Symbol;Acc:HGNC:4712]
Coordinates
chr19:547284-549185:+
Coord C1 exon
chr19:547284-547436
Coord A exon
chr19:548542-548677
Coord C2 exon
chr19:548922-549185
Length
136 bp
Sequences
Splice sites
3' ss Seq
CTGATTCCCTCTGTCCCCAGGAT
3' ss Score
12.14
5' ss Seq
CAGGTGTGC
5' ss Score
6.46
Exon sequences
Seq C1 exon
CTCCTTTGGGACCCAGATCATCGGGGGCCGGGAGGTGATCCCCCACTCGCGCCCGTACATGGCCTCACTGCAGAGAAATGGCTCCCACCTGTGCGGGGGTGTCCTGGTGCACCCAAAGTGGGTGCTGACGGCTGCCCACTGCCTGGCCCAGCG
Seq A exon
GATGGCCCAGCTGAGGCTGGTGCTGGGGCTCCACACCCTGGACAGCCCCGGTCTCACCTTCCACATCAAGGCAGCCATCCAGCACCCTCGCTACAAGCCCGTCCCTGCCCTGGAGAACGACCTCGCGCTGCTTCAG
Seq C2 exon
CTGGACGGGAAAGTGAAGCCCAGCCGGACCATCCGGCCGTTGGCCCTGCCCAGTAAGCGCCAGGTGGTGGCAGCAGGGACTCGGTGCAGCATGGCCGGCTGGGGGCTGACCCACCAGGGCGGGCGCCTGTCCCGGGTGCTGCGGGAGCTGGACCTCCAAGTGCTGGACACCCGCATGTGTAACAACAGCCGCTTCTGGAACGGCAGCCTCTCCCCCAGCATGGTCTGCCTGGCGGCCGACTCCAAGGACCAGGCTCCCTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197540-'3-8,'3-5,4-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.011
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(14.8=96.9)
A:
PF0008921=Trypsin=FE(20.1=100)
C2:
PF0008921=Trypsin=FE(38.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTCCTGGTGCACCCAAAG
R:
TCCAGAAGCGGCTGTTGTTAC
Band lengths:
254-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains