HsaEX6091370 @ hg38
Exon Skipping
Gene
ENSG00000185198 | PRSS57
Description
protease, serine 57 [Source:HGNC Symbol;Acc:HGNC:31397]
Coordinates
chr19:686925-694970:-
Coord C1 exon
chr19:694814-694970
Coord A exon
chr19:691858-692002
Coord C2 exon
chr19:686925-687188
Length
145 bp
Sequences
Splice sites
3' ss Seq
CCACCACCTCCTCCCTGCAGAGA
3' ss Score
10.52
5' ss Seq
CGGGTGAGC
5' ss Score
8.19
Exon sequences
Seq C1 exon
CAGGCTCCTGGGGGGCCCAGATCATCGGGGGCCACGAGGTGACCCCCCACTCCAGGCCCTACATGGCATCCGTGCGCTTCGGGGGCCAACATCACTGCGGAGGCTTCCTGCTGCGAGCCCGCTGGGTGGTCTCGGCCGCCCACTGCTTCAGCCACAG
Seq A exon
AGACCTCCGCACTGGCCTGGTGGTGCTGGGCGCCCACGTCCTGAGTACTGCGGAGCCCACCCAGCAGGTGTTTGGCATCGATGCTCTCACCACACACCCCGACTACCACCCCATGACCCACGCCAACGACATCTGCCTGCTGCGG
Seq C2 exon
CTGAACGGCTCTGCTGTCCTGGGCCCTGCAGTGGGGCTGCTGAGGCCGCCAGGGAGAAGGGCCAGGCCCCCCACAGCGGGGACACGGTGCCGGGTGGCTGGCTGGGGCTTCGTGTCTGACTTTGAGGAGCTGCCGCCTGGACTGATGGAGGCCAAGGTCCGAGTGCTGGACCCGGACGTCTGCAACAGCTCCTGGAAGGGCCACCTGACACTTACCATGCTCTGCACCCGCAGTGGGGACAGCCACAGACGGGGCTTCTGCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185198_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.009 A=0.000 C2=0.091
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(20.0=86.5)
A:
PF0008921=Trypsin=FE(21.3=100)
C2:
PF0008921=Trypsin=FE(38.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCACTCCAGGCCCTACATGG
R:
GGCAGCTCCTCAAAGTCAGAC
Band lengths:
245-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains