HsaEX6091401 @ hg19
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:17556]
Coordinates
chr19:884903-889807:-
Coord C1 exon
chr19:889638-889807
Coord A exon
chr19:885770-886201
Coord C2 exon
chr19:884903-885008
Length
432 bp
Sequences
Splice sites
3' ss Seq
CCTCCCTCCCTTCTCCACAGTCG
3' ss Score
11.27
5' ss Seq
CAGGTGAAC
5' ss Score
5.56
Exon sequences
Seq C1 exon
GCTCCCGGCTCCTGTCAGCAGATGCCGACGGGCAGATCAAGTGCTGGAGCATGGCGGACCACCTGGCTAATAGCTGGGAGAGCTCAGTGGGCAGCCTAGTGGAGGGGGACCCCATTGTGGCCCTGTCCTGGCTGCACAATGGTGTGAAACTGGCCCTGCACGTGGAGAAG
Seq A exon
TCGGGCGCCTCCAGCTTCGGGGAGAAGTTCTCCCGAGTCAAGTTCTCACCGTCGCTCACGCTGTTCGGCGGCAAGCCCATGGAGGGCTGGATCGCGGTGACGGTCAGCGGCCTGGTCACCGTGTCCCTGCTGAAGCCCAGCGGGCAGGTGCTGACGTCCACCGAGAGCCTGTGCCGGCTGCGCGGCCGCGTGGCCCTGGCCGACATCGCCTTCACCGGCGGCGGCAACATCGTGGTGGCCACGGCGGACGGCAGCAGCGCGTCGCCCGTGCAGTTCTACAAGGTGTGCGTGAGCGTGGTGAGCGAGAAGTGCCGTATCGACACGGAGATCCTGCCCTCCCTGTTCATGCGCTGCACCACCGACCTCAACCGCAAGGACAAGTTTCCCGCCATCACCCACCTCAAGTTCCTGGCCCGGGACATGTCGGAGCAG
Seq C2 exon
GTGCTTTTGTGCGCGTCCAGCCAGACCAGCAGCATCGTGGAGTGCTGGTCCCTGCGCAAGGAGGGACTCCCCGTGAACAACATCTTCCAGCAGATCTCCCCCGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221-'3-5,'3-3,4-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(41.0=28.1),PF116353=Med16=PU(90.9=52.6),PF116353=Med16=PU(0.6=3.5)
A:
PF116353=Med16=FE(26.8=100)
C2:
PF116353=Med16=PD(3.0=2.8),PF116353=Med16=FE(11.1=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCGGCTCCTGTCAGC
R:
GGGGGAGATCTGCTGGAAGAT
Band lengths:
271-703
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)