HsaEX6092291 @ hg19
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6714363-6718423:-
Coord C1 exon
chr19:6718258-6718423
Coord A exon
chr19:6718105-6718175
Coord C2 exon
chr19:6714363-6714457
Length
71 bp
Sequences
Splice sites
3' ss Seq
GCCTCTTTGTCTCTCCCCAGTTC
3' ss Score
11.44
5' ss Seq
GAGGTGCCA
5' ss Score
1.44
Exon sequences
Seq C1 exon
ATCCCAGCCAACAGGGAGTTCAAGTCAGAAAAGGGGCGCAACAAGTTCGTGACCGTGCAGGCCACCTTCGGGACCCAAGTGGTGGAGAAGGTGGTGCTGGTCAGCCTGCAGAGCGGGTACCTCTTCATCCAGACAGACAAGACCATCTACACCCCTGGCTCCACAG
Seq A exon
TTCTCTATCGGATCTTCACCGTCAACCACAAGCTGCTACCCGTGGGCCGGACGGTCATGGTCAACATTGAG
Seq C2 exon
AACCCGGAAGGCATCCCGGTCAAGCAGGACTCCTTGTCTTCTCAGAACCAGCTTGGCGTCTTGCCCTTGTCTTGGGACATTCCGGAACTCGTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'4-7,'4-6,5-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0183514=A2M_N=PU(16.7=28.6)
A:
PF0183514=A2M_N=FE(24.0=100)
C2:
PF0183514=A2M_N=FE(32.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGTGGTGGAGAAGGTGGTG
R:
CGAGTTCCGGAATGTCCCAAG
Band lengths:
182-253
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)