HsaEX6092291 @ hg38
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]
Coordinates
chr19:6714352-6718412:-
Coord C1 exon
chr19:6718247-6718412
Coord A exon
chr19:6718094-6718164
Coord C2 exon
chr19:6714352-6714446
Length
71 bp
Sequences
Splice sites
3' ss Seq
GCCTCTTTGTCTCTCCCCAGTTC
3' ss Score
11.44
5' ss Seq
GAGGTGCCA
5' ss Score
1.44
Exon sequences
Seq C1 exon
ATCCCAGCCAACAGGGAGTTCAAGTCAGAAAAGGGGCGCAACAAGTTCGTGACCGTGCAGGCCACCTTCGGGACCCAAGTGGTGGAGAAGGTGGTGCTGGTCAGCCTGCAGAGCGGGTACCTCTTCATCCAGACAGACAAGACCATCTACACCCCTGGCTCCACAG
Seq A exon
TTCTCTATCGGATCTTCACCGTCAACCACAAGCTGCTACCCGTGGGCCGGACGGTCATGGTCAACATTGAG
Seq C2 exon
AACCCGGAAGGCATCCCGGTCAAGCAGGACTCCTTGTCTTCTCAGAACCAGCTTGGCGTCTTGCCCTTGTCTTGGGACATTCCGGAACTCGTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'7-15,'7-10,8-15
Average complexity
S
Mappability confidence:
92%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.006 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0183514=A2M_N=PU(16.7=28.6)
A:
PF0183514=A2M_N=FE(24.0=100)
C2:
PF0183514=A2M_N=FE(32.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGTGGTGGAGAAGGTGGTG
R:
CGAGTTCCGGAATGTCCCAAG
Band lengths:
182-253
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains