HsaEX6092352 @ hg19
Exon Skipping
Gene
ENSG00000141968 | VAV1
Description
vav 1 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12657]
Coordinates
chr19:6832102-6833636:+
Coord C1 exon
chr19:6832102-6832211
Coord A exon
chr19:6833195-6833296
Coord C2 exon
chr19:6833539-6833636
Length
102 bp
Sequences
Splice sites
3' ss Seq
TTTTAATTTTCCCCTGCCAGCTC
3' ss Score
8.73
5' ss Seq
TAGGTGAGA
5' ss Score
6.95
Exon sequences
Seq C1 exon
TGGAGCCACATGTTCCTCCTGATCGAGGACCAAGGTGCCCAGGGCTATGAGCTGTTCTTCAAGACAAGAGAATTGAAGAAGAAGTGGATGGAGCAGTTTGAGATGGCCAT
Seq A exon
CTCCAACATCTATCCGGAGAATGCCACCGCCAACGGGCATGACTTCCAGATGTTCTCCTTTGAGGAGACCACATCCTGCAAGGCCTGTCAGATGCTGCTTAG
Seq C2 exon
AGGTACCTTCTATCAGGGCTACCGCTGCCATCGGTGCCGGGCATCTGCACACAAGGAGTGTCTGGGGAGGGTCCCTCCATGTGGCCGACATGGGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141968-'16-17,'16-16,17-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.088
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(35.3=100)
A:
PF0016924=PH=PD(1.0=2.9),PF0013017=C1_1=PU(39.6=60.0)
C2:
PF0013017=C1_1=PD(58.5=91.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACATGTTCCTCCTGATCG
R:
ATGTCGGCCACATGGAGGG
Band lengths:
197-299
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)