HsaEX6094146 @ hg19

Exon Skipping

Gene

ENSG00000105717 | PBX4

Description

pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]

Coordinates

chr19:19675742-19681108:-

Coord C1 exon

chr19:19680918-19681108

Coord A exon

chr19:19680258-19680393

Coord C2 exon

chr19:19675742-19675898

Length

136 bp

Sequences

Splice sites

3' ss Seq

GAAGGCGGCTGTTTTTGCAGGCG

3' ss Score

4.94

5' ss Seq

CAGGTGACG

5' ss Score

7.66

Exon sequences

Seq C1 exon

GCCTGTCGTGAGTTCACCACGCACGTCACCAACCTCCTCCAGGAGCAGAGCAGGATGAGGCCTGTCTCCCCTAAGGAGATTGAGCGCATGGTCGGCGCCATTCACGGCAAGTTCAGCGCCATCCAGATGCAGTTGAAGCAGAGCACCTGTGAGGCAGTGATGACCCTGCGTTCGCGGCTGCTCGATGCCAG

Seq A exon

GCGCAAGCGGCGGAATTTCAGCAAGCAGGCGACGGAAGTGCTGAATGAGTATTTTTACTCCCATCTGAACAACCCTTACCCCAGCGAAGAAGCCAAAGAAGAGCTGGCCAGGAAGGGCGGCCTCACCATCTCCCAG

Seq C2 exon

GTCTCTAACTGGTTTGGCAACAAAAGAATCCGGTATAAAAAGAACATGGGGAAGTTTCAAGAAGAGGCTACCATTTACACGGGTAAAACGGCTGTGGATACCACGGAAGTTGGGGTCCCAGGGAACCACGCCAGCTGCCTGTCAACACCTAGCTCCG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000105717-'4-5,'4-4,5-5=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.234 A=0.239 C2=0.528

Domain overlap (PFAM):

C1:

PF037928=PBC=PD(30.8=95.3),PF0076914=ERM=FE(39.1=100),PF070286=DUF1319=PD(62.5=85.9),PF040917=Sec15=PD(63.4=81.2),PF0044324=UCH=FE(25.8=100),PF0004624=Homeobox=PU(0.1=0.0)

A:

PF0076914=ERM=FE(28.0=100),PF0044324=UCH=FE(18.4=100),PF0004624=Homeobox=PU(75.0=97.8)

C2:

PF0076914=ERM=PD(12.4=37.7),PF0044324=UCH=FE(21.3=100),PF0004624=Homeobox=PD(21.7=24.5)

Main Inclusion Isoform:

ENSP00000251203f2406A