MmuEX0033856 @ mm9
Exon Skipping
Gene
ENSMUSG00000031860 | Pbx4
Description
pre B cell leukemia homeobox 4 [Source:MGI Symbol;Acc:MGI:1931321]
Coordinates
chr8:72388723-72394583:+
Coord C1 exon
chr8:72388723-72388913
Coord A exon
chr8:72390367-72390502
Coord C2 exon
chr8:72394477-72394583
Length
136 bp
Sequences
Splice sites
3' ss Seq
CTGGGCATCTCTGTCTGTAGGCG
3' ss Score
7.65
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GCCTGTCGTGAGTTCACCACACATGTCACCAACCTTCTCCGGGAACAGAGTAGGGTGAGGCCTGTGTCTTGCAGGGAGATGGAACACATGGTGAACACCATCCAGAGCAAGTTCAGTGCCATCCAGAGGCAGCTGAAGCAGAGCACGTGTGAGGCTGTGATGACTCTACGCTCACGGTTCCTGGATGCCAG
Seq A exon
GCGCAAGCGGCGGAATTTCAGCAAGCAGGCCACAGACGTGCTGAATGAATATTTCTATTCCCATTTGAGCAACCCTTACCCCAGTGAAGAGACCAAAGAAGAGCTGGCCAGGAAGGGTGGCATCACAGTGTCCCAG
Seq C2 exon
GTCCCTGTGGCCCCTTGCCACTGACCAATGGAAGTGACGTGGTTCTCACTCTGCGGACCCTGGCCTTCCTCCAGCCCCCCACTGGGGGAGTCTGCCTACAGCCCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000031860_MULTIEX1-4/5=3-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.076 A=0.302 C2=0.194
Domain overlap (PFAM):
C1:
PF037928=PBC=PD(31.1=95.3),PF070286=DUF1319=PD(31.6=85.9),PF040917=Sec15=FE(67.7=100),PF083976=IMD=FE(51.2=100),PF0004624=Homeobox=PU(0.1=0.0)
A:
PF040917=Sec15=PD(0.1=0.0),PF083976=IMD=PD(26.8=71.7),PF0004624=Homeobox=PU(75.0=97.8)
C2:
PF037928=PBC=PD(3.5=5.4)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACAGAGTAGGGTGAGGCCT
R:
CTGTAGGCAGACTCCCCCAG
Band lengths:
250-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types