HsaEX6094692 @ hg19
Exon Skipping
Gene
ENSG00000105254 | TBCB
Description
tubulin folding cofactor B [Source:HGNC Symbol;Acc:1989]
Coordinates
chr19:36611612-36616425:+
Coord C1 exon
chr19:36611612-36611708
Coord A exon
chr19:36612429-36612620
Coord C2 exon
chr19:36616353-36616425
Length
192 bp
Sequences
Splice sites
3' ss Seq
CCAGCCCCCTCTGCCCACAGACA
3' ss Score
10.27
5' ss Seq
TAGGTGCGT
5' ss Score
6.6
Exon sequences
Seq C1 exon
GTCATTGACCACAGTGGCGCCCGCCTTGGTGAGTATGAGGACGTGTCCCGGGTGGAGAAGTACACGATCTCACAAGAAGCCTACGACCAGAGGCAAG
Seq A exon
ACACGGTCCGCTCTTTCCTGAAGCGCAGCAAGCTCGGCCGGTACAACGAGGAGGAGCGGGCTCAGCAGGAGGCCGAGGCCGCCCAGCGCCTGGCCGAGGAGAAGGCCCAGGCCAGCTCCATCCCCGTGGGCAGCCGCTGTGAGGTGCGGGCGGCGGGACAATCCCCTCGCCGGGGCACCGTCATGTATGTAG
Seq C2 exon
GTCTCACAGATTTCAAGCCTGGCTACTGGATTGGTGTCCGCTATGATGAGCCACTGGGGAAAAATGATGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105254-'5-8,'5-4,9-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=0.412 C2=0.000
Domain overlap (PFAM):
C1:
PF145601=Ubiquitin_2=PD(16.3=21.2),PF047957=PAPA-1=PU(26.3=60.6),PF050938=CIAPIN1=PU(19.8=57.6)
A:
PF047957=PAPA-1=PD(72.4=84.6),PF050938=CIAPIN1=FE(66.7=100),PF0130220=CAP_GLY=PU(31.4=33.8)
C2:
PF050938=CIAPIN1=PD(12.5=48.0),PF0130220=CAP_GLY=FE(39.3=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCATTGACCACAGTGGCGC
R:
CTGCCATCATTTTTCCCCAGTG
Band lengths:
170-362
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)