HsaEX6099677 @ hg38
Exon Skipping
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127396532-127402682:+
Coord C1 exon
chr5:127396532-127396778
Coord A exon
chr5:127398676-127398796
Coord C2 exon
chr5:127402546-127402682
Length
121 bp
Sequences
Splice sites
3' ss Seq
GTCACATGTTAATCCCTCAGCTG
3' ss Score
5.38
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
Exon sequences
Seq C1 exon
CCTGCGATGGTGATCACTGGGGTCCCCACTGCACCAGCCGGTGCCAGTGCAAAAATGGGGCTCTGTGCAACCCCATCACCGGGGCTTGCCACTGTGCTGCGGGCTTCCGGGGCTGGCGCTGCGAGGACCGCTGTGAGCAGGGCACCTATGGTAACGACTGTCATCAGAGATGCCAGTGCCAGAATGGAGCCACCTGCGACCACGTCACGGGGGAATGCCGCTGCCCACCAGGATACACCGGAGCCTT
Seq A exon
CTGTGAGGATCTTTGTCCTCCTGGTAAACATGGTCCACAGTGTGAGCAGAGATGCCCTTGTCAAAATGGAGGAGTGTGTCATCACGTCACTGGAGAATGCTCTTGCCCTTCTGGCTGGATG
Seq C2 exon
GGCACAGTGTGTGGTCAGCCTTGCCCCGAGGGTCGCTTTGGAAAGAACTGTTCCCAAGAATGCCAGTGCCATAATGGAGGGACGTGTGATGCTGCCACAGGCCAATGTCATTGCAGTCCAGGATACACAGGGGAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794-'16-12,'16-10,17-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PU(84.6=13.3)
A:
PF126612=hEGF=PD(7.7=2.4)
C2:
PF079748=EGF_2=PU(93.5=63.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGCAAAAATGGGGCTCTGT
R:
TTCTTTCCAAAGCGACCCTCG
Band lengths:
249-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains