HsaEX7005614 @ hg38
Exon Skipping
Gene
ENSG00000136877 | FPGS
Description
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]
Coordinates
chr9:127807586-127808705:+
Coord C1 exon
chr9:127807586-127807688
Coord A exon
chr9:127808234-127808311
Coord C2 exon
chr9:127808558-127808705
Length
78 bp
Sequences
Splice sites
3' ss Seq
TCTCCTTCTTCCCTCCACAGCAA
3' ss Score
11.75
5' ss Seq
TCAGTAAGT
5' ss Score
9.14
Exon sequences
Seq C1 exon
GAAGCCTGTGGTGTGCGGAGTCTCCTCTCTTGGCATCGACCACACCAGCCTCCTGGGGGATACGGTGGAGAAGATCGCATGGCAGAAAGGGGGCATCTTTAAG
Seq A exon
CAAGGTGTCCCTGCCTTCACTGTGCTCCAACCTGAAGGTCCCCTGGCAGTGCTGAGGGACCGAGCCCAGCAGATCTCA
Seq C2 exon
TGTCCTCTATACCTGTGTCCGATGCTGGAGGCCCTCGAGGAAGGGGGGCCGCCGCTGACCCTGGGCCTGGAGGGGGAGCACCAGCGGTCCAACGCCGCCTTGGCCTTGCAGCTGGCCCACTGCTGGCTGCAGCGGCAGGACCGCCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136877-'16-35,'16-33,21-35=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.140
Domain overlap (PFAM):
C1:
PF082457=Mur_ligase_M=FE(16.0=100)
A:
PF082457=Mur_ligase_M=FE(11.7=100)
C2:
PF082457=Mur_ligase_M=PD(17.8=76.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTCTTGGCATCGACCACAC
R:
GTTGGACCGCTGGTGCTC
Band lengths:
172-250
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains