HsaEX7006505 @ hg38
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:HGNC Symbol;Acc:HGNC:16063]
Coordinates
chr10:21612348-21617207:+
Coord C1 exon
chr10:21612348-21612451
Coord A exon
chr10:21614831-21614924
Coord C2 exon
chr10:21617112-21617207
Length
94 bp
Sequences
Splice sites
3' ss Seq
TACTTGGCTTTTATTTTCAGCGC
3' ss Score
7.71
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
ACTTGCTACATTTGTGATGAACAAGGAAGAGAAAGCAAAGCAGCCACTGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATG
Seq A exon
CGCTCAGTTTGCCGGACTGCTTTGTGAAGAAGAAGGTAATGGTGCCGATAATGTCCAATACTGTGGCTACTGTAAATACCATTTTAGTAAGCTG
Seq C2 exon
AAAAAGAGCAAACGGGGATCTAATAGGTCATATGATCAAAGTTTAAGTGATTCTTCCTCTCACTCTCAGGATAAACATCATGAGAAAGAGAAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-'54-45,'54-43,58-45=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.835
Domain overlap (PFAM):
C1:
PF138321=zf-HC5HC2H_2=FE(28.8=100)
A:
PF138321=zf-HC5HC2H_2=PD(22.9=84.4),PF105004=SR-25=PU(30.7=71.9)
C2:
PF105004=SR-25=FE(41.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGAAAGCAAAGCAGCCACT
R:
TCTCTTTCTCATGATGTTTATCCTGA
Band lengths:
168-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains