HsaINT0001797 @ hg19
Intron Retention
Gene
ENSG00000143322 | ABL2
Description
v-abl Abelson murine leukemia viral oncogene homolog 2 [Source:HGNC Symbol;Acc:77]
Coordinates
chr1:179095512-179100616:-
Coord C1 exon
chr1:179100446-179100616
Coord A exon
chr1:179095808-179100445
Coord C2 exon
chr1:179095512-179095807
Length
4638 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
TGTGATGACCTTATGGCTAGGTG
3' ss Score
5.47
Exon sequences
Seq C1 exon
AAGCTTTGCATCGTCCCTATGGTTGTGATGTTGAACCCCAGGCACTAAATGAGGCTATCAGGTGGAGCTCCAAGGAGAACTTGCTCGGAGCCACTGAGAGTGACCCTAATCTCTTCGTTGCACTTTATGATTTTGTAGCAAGTGGTGATAACACACTCAGCATCACTAAAG
Seq A exon
GTGAGGCTTCTATGTAGCATCCTTTCACTTTTCAGTTTTCATTAATGATTAAGAGATAAAGGGGCCTGGCCAGGCACAGTGGCTCACACCTATAATCTCAGCACTTTGGGAGGCCAAGGCGGGCAGGTCACCTGAGGTCAGGAGTTTGAGACCAACCTGGCCAACATGGTGAAACCCTGTCTCTAATAAAAATATGAAAAAAATTAGTCAGGCGTGGTAGCCCATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCATGAGAATCACTTGAACTCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAGAAAAAAAAAAAAAAATTATCCTGAAATACATTTTTTTCCCCGGCAGTGGCTTTCATATGTTCAAAAGGTAAGAATAAGCTTAGGCAGACTAGCAATCCAGTTCATGTACACAAGGATAATCTCCCCATAATCCTATTTCTTTCTCATAAAAGTTACTTTTTTTTGCCTTTGCATGCGTGTGTGCGTACACACACACACACACACACACACACACACACACACACAAAATCAATAATGATTGATTTTATTTGGTCATGTTCTTAATGTTCCCTTTTATAAGAATTTCCCACGGAAATAAACTACCACTCTCTTGAGAATATTACTATAATGGAAATCAAATAAACCTTTCCTACCATTCCTTTCACTAATCTATATAAACACAAACAATAGACATTTATGTTGTCTAGGCCAGTGCTACTCAAAAATGGTCCACAACAAGGTAAGATGCTTATGCCAGAATGTGAAACACTGAACTACTATCTTCATGCAGAAAGCCTTGCTCCAAAAGGTAAAACTATTAGCTGAACTAAGTAATAAATAGTGTGCTTAGTGATATAGTTGGTTTACATTTAGTTGAAGTTCTTAATCTCACTGTGGACTAGTAATGAATGAACAGTCCTCAGATAGGCAGTCAAGTTCGCAGACATTCTGAGTAGCAGTGAGGTCTGGCAACATGGCTCATCTTAGCCACAGTTCAATTAGAATAGGTGTGACCAGGCACAGTGGCTCACGCCTGTAATCTAGCACTTTGGGAAGCCGAGGCTGGTGGATTGTCTGAGCTCAGGAGTTTGAGACCAGCCTGGGCAACACGGTGAAACCCCATCTCTACTAAAATACAAAAGACATTAGCCGTGTGTAGCGGCATGTGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGGATAATTGCTTGAACTTGGGACGGGGAGGTTGCATTGAGCTGAGATGGTGCCACTGCACCCCAGCCTGGGCGACAGAGTGAGATGCCGTCTCTTAAAAAAACAAAAACAAAAGAATAGGTGTATAGTGAGTCTAACCTTCATGGTAGTTGCATGTGCTGGCCAATTGTACATAGGACAGAATTAAAAGTGAAAGTAAAAGTGCATCATCTCCTAGTGTCAGTTTTACTTCCTGCTTTTGGATAGTTTTGGGGACAGGATGATACATGTTATGTATGTGGGGGTTGTGTTTATGCAGTTGTAGGAACATTTTACGTAAAATTTGAGGATAGAACAAAAGACATCAAAGAATTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAGTCTCGGCTCACTGCAAGCTGTGCCTCCTGGGTTCAAGCGATTCTGCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGCACCACCACGCCGTGTTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCCATGTTGGTCAGGATGGCCTCGAACTCCTGACCTGTGATCCACCTGCTTCAGCCTCCCAAAGTGCTGGGGTTACAGGCGTGAGCCACCACGCCCAGCCAGAAAGTTTATATTGTGTAGTAGTCTCTTTGGACTACAATATACTTGATTTTACCTTTATTGATTCTTCACTGGAGAAATTTGTGAAGTGATGACTCAGAAATTCTTTCATAGGTATGTTTTCCTGTTGTTTTTTCAAGATAGCCCAGTCATCAAGGAAACATTGATAAAGAAAGACTGTTGATTCCTCACTTATGGGTTATGACTGGCCTTTATCTTATGACCAACAGTGGTTTCTCTTAAAATCCACAGAATGCCAAATTTTTATATCAGGTTCTCACTAATTTAAAATGATGTCATACTAAAGCTATTTTATTATTTTAAAAGACAAGAAAATATATTTAAAAAATAAAGCAACACTTTAGTTTTTGATTGAAAATGATATTTTGCTTGAATTTTTTTTTTTTAAAGTTCTACCAGCCAAGCGCAGTGGCTCATCCCTGTATTCTCAGCACTTTGGGAGGTTGAGGCAGGAGGATTGCGTGAGCCTAGGAGTTCAAAACCAGCCTAGGCAATGTAGTGAGACCCCTGTCTCTACAAAAAATTTAAAAATTAGCCAGGGGCAGTGGCATGCACCTGTAGACCCAGGTACTTGGGGGGCTGAGGTCTGAGGATCACTTGAGCCTGAGAAGTTGAGGTTACAGTGAGCTGTGTTTGCACCGCTGCACTGCCGCGTGGCGACAGAGGGAGACCTGTTTCAAAACAAACAAAAAAGTTCTCCCTAGGGTTGCTCTGCCAGTTTGGCCAATATTTGAATCCATACTAGTCATCCCCCTATCAGTTTCCATGGTAGTCAAAACTTCCAGGGTAGAAAAATTTTCCTGATAACTGACAAAAAAAGAACAACAAACAAAAAATCCTGGGGTCTTTGACTGTATCTTAATTATGATAGCCTGTTATTACCAATTCTTTTCAAGGAAGCAACAATATTAAAAAATGTATATATAGATATATATACAAAGTACTAATATTCTTTATTTTTAGCTCATGTGGACTAACAGAGAAAAGCTACAGAGCAACAGGTTTTCTTCAGTTTTTCTAGCAGGATTCTTTTTTTTTTCTTCCTGTAAATATGATTGGCAAGTATTTGTGCACTTATGCATATCCACCGCTACACCAGACTTACTCTTATCTGTATATATGTATATTTTATGTACCCATAGGTGTATATATGTACATATACTCTTGTGTTTTTTCTCATTATCTCATATCCATGTGTCTAAGGTGAGATGGTGTCTGATACAAAGTTATTCTATGGAAACGTTTCTGAAGGCCACTAAAAAAGGACAGATGGTTACAAGGATAATTATTTTTAGTTCTCCTAAAAACTTTTGCCTGATACTTCTGGCCATGTGCTTTTTTTTTTTTTTTTAGCAGTCTCACTCTGTCTCCCAGGCTGGAGTACAGTGGTGCAATCTCGGCTCACTGCAACCTCAGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCAGACTATCACACCCGGCTAATTTTTTGTATTTTTGGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGTTTTGAACTCCTGACCTTAGGTGATCCGCCCCTCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGACACCACGCTCAGCCATGGCCATGTGCTTTTGATTGACTTGGCTTCCTTCTACTTTTTGACACTGAAGAAGTAGATGTGAATGCTGTAGGAAGACTTGCATCTCTTAGAGATAAGAGCCTGAGGCACTACAAGGATTCTTTAGATTAGCATTTATTTATCACTAGTGATATCTCTTTCACTTTTTCTGTTTTGTCAAAGAAACCTAATTTGTGCTGCAAGTATCGGGGCAAGTTATATGTTGAAGTCTGAACTTGATGTTCACAATTTTAATAGAAAAATTAAGAACATTGAAGTTGACAGCAAAGATACACTGAGTGACTTGGGTTTTGGTTTCCAACTTCAGAGTGAGCTTGCCATTCCACACACTGATTTTAATGTGGAATGGAAAGGAGTGATTCATTCTTTGTGGGAACTAGGAAGGAAATAAGAAAGCTATAGCTATTTTTAAACTTGCATTCTGGAAGGGATTGTGTTTTGGGAGTCCTAACTGCCCATTCCCCTCACCCCACTAAACAGTTTTCTTGCTGAAAACTCTGTGGTCCGTGTTTTTTTTTGTTTGTTCATTTTTTGTTTTTGTTTTTGTTTTTTTACATCAGTGGTTTTGTTGCCTTGGTGCCAAGTGAAATTTAGAAGTCACTTTGTATCTCACATGTCTTATCCCTAATCCTTGATTGTTGTTAACATTGAATCATATATAAGATACATTCCTTGATAAACTTTTGAGGGAAAGTGAATTTTCTTCTTTTGAAGAGTGAGCACTGTGTCCTTTTCCAGCCATTTTAGTAACCTGTCTGGCATACATAGAATTTCTTAAGGATATTTTTTAAGTTGTATATAGACTTTTAAAACCCTGTAGTAAATGCCAGAAAACCATTTGTGACCATACTTCTGTGGTTAAGCTAAAAGCTAAAGAGAGCAATCAGGATATGATGAACAGCCAAGTTTGTTTTCATTATTTAAAAAAAAAATTTGGCATAAAAGTTCTAGATTCTTTTTTTTTTTTAATGAGTTTAAAGTTTGACAGTACACTGCTTCAGTTGAAATAAAGTCTTAACATCGTTTCTTTCATCCTGTGATGACCTTATGGCTAG
Seq C2 exon
GTGAAAAGCTACGAGTCCTTGGTTACAACCAGAATGGTGAGTGGAGTGAAGTTCGCTCTAAGAATGGGCAGGGCTGGGTGCCAAGCAACTACATCACCCCAGTGAACAGCCTGGAAAAACACTCCTGGTACCATGGACCTGTGTCACGCAGTGCAGCTGAGTATCTGCTCAGCAGTCTAATCAATGGCAGCTTCCTGGTGCGAGAAAGTGAGAGTAGCCCTGGGCAGCTGTCCATCTCGCTCAGGTACGAGGGACGTGTGTATCACTACAGGATCAATACCACTGCAGATGGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143322-ABL2:NM_001168236:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.097 A=NA C2=0.010
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PU(38.3=31.0)
A:
NA
C2:
PF0001823=SH3_1=PD(59.6=28.3),PF0001719=SH2=PU(73.7=56.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)