HsaINT0003385 @ hg38
Intron Retention
Gene
ENSG00000114739 | ACVR2B
Description
activin A receptor type 2B [Source:HGNC Symbol;Acc:HGNC:174]
Coordinates
chr3:38479128-38479826:+
Coord C1 exon
chr3:38479128-38479271
Coord A exon
chr3:38479272-38479677
Coord C2 exon
chr3:38479678-38479826
Length
406 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
TCTGTGCTGTCTTCTCTCAGGGC
3' ss Score
11.86
Exon sequences
Seq C1 exon
GACAAGCAGTCGTGGCAGAGTGAACGGGAGATCTTCAGCACACCTGGCATGAAGCACGAGAACCTGCTACAGTTCATTGCTGCCGAGAAGCGAGGCTCCAACCTCGAAGTAGAGCTGTGGCTCATCACGGCCTTCCATGACAAG
Seq A exon
GTGAGCCACACCCATCAGAATGGACTCTGAGAGGAGATGGAATGTCCCCTTGGTGGCTCTCCATAATATGATGACCCCTTCCCTGTGGAGGTGTCCACCATGAAGTACTCTGCCCCGGTAGCACTATCCACTATGGGGTTACTCCTGCCATAGGTGTGGACATTGGTTCCCCTATGATAGGAACCTCTCACCCTGGGATAAGTTTTTATGATAAGAGTAGTGACTCCATGATTCCCACCCCTAGCCCTCCCTGCCTCCTGGCCTCATCCATCTTCCATATCGATTGTAGTAGCCTTCCAGGAGAGCAGCCTAGCCATTGGCCCACTGAGACTTCTCTGCCAGGGCTGGGCTGGGTCCTGTCCTGTACCCAGAATCTGTGCTCAAGTTCTGTGCTGTCTTCTCTCAG
Seq C2 exon
GGCTCCCTCACGGATTACCTCAAGGGGAACATCATCACATGGAACGAACTGTGTCATGTAGCAGAGACGATGTCACGAGGCCTCTCATACCTGCATGAGGATGTGCCCTGGTGCCGTGGCGAGGGCCACAAGCCGTCTATTGCCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000114739:ENST00000352511:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.3=100)
A:
NA
C2:
PF0006920=Pkinase=FE(17.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCAGTCGTGGCAGAGTGAA
R:
CTGTGGGCAATAGACGGCTTG
Band lengths:
290-696
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development