MmuINT0010624 @ mm10
Intron Retention
Gene
ENSMUSG00000061393 | Acvr2b
Description
activin receptor IIB [Source:MGI Symbol;Acc:MGI:87912]
Coordinates
chr9:119429865-119430368:+
Coord C1 exon
chr9:119429865-119430008
Coord A exon
chr9:119430009-119430219
Coord C2 exon
chr9:119430220-119430368
Length
211 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
AGTCTGCTGCCTTCTCTTAGGGC
3' ss Score
8.61
Exon sequences
Seq C1 exon
GACAAGCAGTCGTGGCAGAGTGAACGGGAAATCTTCAGCACACCCGGCATGAAGCACGAAAACTTGTTGCAGTTCATTGCTGCCGAGAAACGAGGCTCCAACCTGGAGGTGGAGCTGTGGCTCATCACAGCCTTCCACGACAAG
Seq A exon
GTGAGCCACACCCCAGACAGATCCCACGGTGAGATAGATGGGTCCCAGTGATGGTTTTGTGATGAGCTGACCCCGTGTCAGCCGCACTTCCCACCTGGATCACGTCCGCCCATTCTGCGCATTTGCACTGAGACGTTCCTGCTGGGCCTGGGTTGGTTGCATCCTGTTCTGCATTTGGAGCCTTTGCCCACAGTCTGCTGCCTTCTCTTAG
Seq C2 exon
GGCTCCCTCACGGATTACCTCAAGGGGAACATCATCACGTGGAACGAACTGTGCCACGTGGCGGAGACGATGTCACGAGGCCTCTCATACCTGCATGAGGATGTGCCGTGGTGTCGTGGTGAGGGCCACAAGCCTTCTATTGCCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000061393:ENSMUST00000165044:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.3=100)
A:
NA
C2:
PF0006920=Pkinase=FE(17.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAAGCAGTCGTGGCAGAG
R:
TGTGGGCAATAGAAGGCTTGT
Band lengths:
292-503
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types