HsaINT0005077 @ hg38
Intron Retention
Gene
ENSG00000181026 | AEN
Description
apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]
Coordinates
chr15:88626146-88629426:+
Coord C1 exon
chr15:88626146-88626749
Coord A exon
chr15:88626750-88629225
Coord C2 exon
chr15:88629226-88629426
Length
2476 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
3' ss Seq
ACTCCTCTTTCTGCTCACAGATC
3' ss Score
11.64
Exon sequences
Seq C1 exon
GCTGCTGCCCCATTGGAAGATTACTCCCCAGGCTTCCCTTGCCCCAAGCAGTGAGCTGACTGGAATGGTACCCCGGGAGGCCCCTGAGTCTGCTCAGTGCCTGTGCCCTTCCCTCACCATCCCAAATGCCAAGGATGTGCTTCGGAAGAGGCACAAGAGAAGGAGCCGACAGCACCAGCGGTTCATGGCCCGGAAGGCCTTGCTGCAGGAGCAGGGGCTGCTGAGCATGCCTCCAGAACCAGGGTCCTCCCCACTGCCCACCCCTTTCGGGGCAGCGACAGCAACTGAAGCTGCCAGCAGTGGGAAGCAGTGTCTGAGGGCTGGATCTGGCAGTGCCCCATGCAGCAGAAGGCCTGCTCCCGGGAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTGTGGCTATCGACTGTGAGATGGTGGGCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCCGCTGTTCCATTGTGAGCTACCATGGCAATGTCCTCTATGACAAGTACATCAGGCCTGAGATGCCCATCGCTGACTACCGTACCCGCTGGAGTGGCATCACTCGGCAGCACATGCGCAAGGCTGTCCCCTTCCAGGTGGCCCAGAAAGAG
Seq A exon
GTAAGGGCAGGGATGGGGACTTGTTTGGGAGGTGTGGTGGGCTGGAAAGAGCCACCCTGGGTTTGAATCACCACTTTGCTTCACTGGGGGCAAGAAACCTTGGGAAAGTCACCTAACTGCTCCAAACAGTAGGTTCCTTCTCCATAGAACAGGGGAAATAAAAATAAAATCCTGACCTTGCCTCCAGATAAGGATTGCTGGCCTGTTGCACAGGACAATGTAGAAAGGCTACACCAACTGTAAGGTGATAAATAGCTTACATTTTAGAGTTTGCTTTCTGTTATAAAAGTTGTACGCATTGATATAAAATTTGTAAAGCCCACAGTGGCATCACGTTCAGGTATGGATGTTTTGGCATATTTCCTTATGTTAGTTTCTTAGTGCTTAGAAAAAATTAATTAGTGGTTGGGACCACACTGATGCACCAGGAATTCCCAAACATGCTTGACCTTAGAAACACCTAAGTCCTTTTTAACAATCTAGGATCCTTGTCCCCAGTTCCCTCCATAGAGTTCCTGATCCATTAGGCTTGGGGAGGGCTCTGACCCATGTTCCAAAAAATCATCACACTGTGTAGACTTGCACCATAAAGCCACAGGGCTTAAGGGGAAATGGAGAAAGGGAACAGTATTAAAAAGGCCATCAGTGACACCCCAAAAATAAGATAGAAACCTAATAAAAAGGTAGTCCAGTTTTACGCATCTTGTTTCTTTTTTTTTTTTTTTTTATTCCACACATCTTAAATGGTTAAGAAATGCACAATACACCAATAAGTATGGCACTTTACCTTGAAAAAGACCTGAACTTGCTTGTGGAAAGAGGAGTCAGAAAGGTTGCAGCTTGAGTTTCTGTGAAGTGGTTGAAGGAGAGTTCTTTGAAGTCAGACAGGAAGTGTGACACCAGCTGTGGATGGGTGTGGCTCATCACACAGGTGAACTAGGGTTGCTGGGAGATGTTTGGGCTGTGTGCATATTGTGTATGCCCTCTTGGCTTAGTTCAGTTGGATGCAGTTTTCTGCGTTCATTCAGTGTTTCTCAAGGATGAAATTATGCACAAGCAAAGGTGAAATTTGCATTGTTCTCAAAATGTGTCATACATCAATTGCATTGAGACAAATCTGCATTTTCTAAACAAGCCTTGTAACAGAACCACTTTTTAACACTTCTGGGTTATTCTTGGGATTAGGCAAGGTTGGGAAATACTGGTGTACACTATCTCGTGTCCTACTTTTTCACATAACATTGTGGCCCGAGCATTCCTTTGAAATGATCGGAGGTTATTTTATGTATCAAGCAGGCCAATCAGTAAGAGTAGCAACAAGAGGGGAGGTGTGTGGTGAACCCTCCAGCTCCTTGGTCCCTTCCATTGACCTGGTTGGTGGTGGTCCCAAGAGCAGGACCACTTTTTGTCTGCCCAGACTCCGAGCCACTGTGGGTTGTGCTTCATCTCTTTCCACTTCATGGCTGACTTGGGGGGAGGGGCAGTGTGGTGAGTGACCAGCATGGTGGCATGTCCCTACTATAAAGTCTCAATGCATCTTATCCATCTGCCATGAAAGCTGGGTTTGGGGATAAACATATGTTGCCAGCAGAGGTAGGCTGTGGAGGCCCGCAGCTGGTGATAAGGAGAGCCCAAGCCCAGCTAAGAGGGCTAGAGGGGGTTGCTGGCCCATGGCCCTGGGCGTGGCCTCCCTGGTGTATGAGGAGGGCCACCCAGCAGGGAAGGGAGGTACACATTGTGCAGGCAGCCAGAGCTGAGCAAGAGAGCAGGTTAAGAGGATGAGGAGGAGTTGGTACACAGCAGGGCAAGGGGGCAGAGTCCTGAAGACAGGGATTATGGCCCTTAATGCTCATAAGAGCTGCTGCTATGGTGTGTCTACCAGTGACAGGCACGGTTCTGTTGACTTCACCCAGCTGGTCTTTATTGATCACCTCCTGTGATAAGTAAATAATCAATAAATGTAATGCTTTCTACTACAGGAAAAAGATAGGCATTAAAAAAAAAGAATAAATGTGACGCTTTCCTTGGAGCATCACTAAGAAGTCCAACATGGTCCCTGCACTCACAGACCTTACAGTGCGGTGGGGGAGAGTTGGGTGGAGTGGGAGGCCTGGTGACGTCTTCCAGGCTGAGAGGAGAGCCAACACCAGCAATAGAGTTGCTTGTATCTGGTAACAGGAAGACTTCCATCCATGACCTCGTTTAGTCCTTAGAGCCACCCCACGGAATGCTGCTGGCAGTGTTTCCCTTTGACAGGTGCAGAAGACATAGGTATGCCCCTGGGTATAGACAGTAGAAGGGTCTGGGTTCAGACTTGGGGCAGCATGGTTGACTGTGGAGCTCGTGATCTCCCCACTCGGTGCTGCCTCCCCCCACAGGGATCCATGCATCTATTGGCCAGGGGTTCTCAGGGCGTGTCTCCTGCCAACCTGATGGGGTGTGGGGTGACCTCCCTGACTCCTCTTTCTGCTCACAG
Seq C2 exon
ATCCTTAAGCTCCTGAAGGGCAAGGTGGTGGTGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGACCCGGGATACGACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTCTAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181026:ENST00000332810:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.428 A=NA C2=0.075
Domain overlap (PFAM):
C1:
PF0092919=RNase_T=PU(44.2=38.3)
A:
NA
C2:
PF0092919=RNase_T=FE(42.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development