HsaINT0008093 @ hg19
Intron Retention
Gene
ENSG00000145362 | ANK2
Description
ankyrin 2, neuronal [Source:HGNC Symbol;Acc:493]
Coordinates
chr4:114213572-114214694:+
Coord C1 exon
chr4:114213572-114213670
Coord A exon
chr4:114213671-114214595
Coord C2 exon
chr4:114214596-114214694
Length
925 bp
Sequences
Splice sites
5' ss Seq
GCGGTAAGG
5' ss Score
9.63
3' ss Seq
CTCTTTCACTCTCTCTTCAGAAT
3' ss Score
11.67
Exon sequences
Seq C1 exon
AACGGCTACACGCCTTTGCACCAGGCCGCTCAGCAGGGTCACACGCACATCATCAACGTCCTGCTCCAGCATGGGGCCAAGCCCAACGCCACCACTGCG
Seq A exon
GTAAGGCAGACGCCACTGCCCCTCACCACGCTTTCTTCTTTTTCCTCTCTTGCCCTGGTGGCTTCTTGTCTGAGCTGAGTGAGGTCAGATTCCTCCTCTTTAAATAAGCCCCCTGGACTCTGGAAAGCCCCAGATTTTTGGGCAGGCTTTCCAGAAGTCAGTGTGACTTCCCCAGAAGTGCTTGCCCTGGGAGGGAAAGCAGTCAGCCTGACTCTTTGGCTCTCTCTGGAGACGGGGGCCCTCCGCTTGGGCTGCTGGAACGTGCTCTGCTTACAGCTGGCTCTCAGATGTGAGCACAAATTGACCCCCCCTCGCCTTCTTAAGGGAGCACAGTAAGGGAGCTGCTAGCTTAAACAAAGCTCATTGAGTTGTGGAGCCATTGAAATGTAAACTAAGCGGTGCAATTAAACGAACTGGGATCCCGAGTGGCCTGGGTTGGATGCAGCCCGAATTGCTTGCCTGTGTTATTTTGCTGCACAGTGAGCTTCTGCACAGCTGTAGCTAAATATGTTACCGTGTTCCCGATGGTAACATCTTACCTGCAGCAGATGGCCTGACTTCTGATGAGGGATAAGTGTACCTGGTACTTGCTAACAGGTTTTGGAGACGTCATGAGGCACTTTCTTAAGTGCAATACAGTATTTGTAGAAGATATTTGACAACCTTAGGGTTAAAGCGTCAAGTGCTTCTTATTAAAAAGAGCAAGCAGATGCAAGCTTGTTGTGTTACCATGGTGACCTGGCCTATAGTCTGAAGAAGTTACAAAGACAGATTTAGACGTAATGGTAAAAACTAGTGATTTTCCTAAGCTGTGCCTTGTTTTGGAAGGAAATGCTGGCTGATGCAGAGCAGCGGGTGAGCTCATTGGCTCACATCGCAGTCCTCTCTCTTATTTCTCACTCTCTCTCTTTCACTCTCTCTTCAG
Seq C2 exon
AATGGCAACACTGCCTTGGCGATTGCTAAGCGTCTGGGCTACATCTCCGTGGTCGACACCCTGAAGGTTGTGACTGAGGAGGTCACCACCACCACCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145362-ANK2:NM_020977:21
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.394 A=NA C2=0.126
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(32.6=90.9)
A:
NA
C2:
PF127962=Ank_2=PD(41.8=84.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTACACGCCTTTGCACCAGG
R:
TGGTGGTGGTGGTGACCTC
Band lengths:
191-1116
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)