HsaINT0018493 @ hg19
Intron Retention
Gene
ENSG00000169925 | BRD3
Description
bromodomain containing 3 [Source:HGNC Symbol;Acc:1104]
Coordinates
chr9:136910415-136913576:-
Coord C1 exon
chr9:136913205-136913576
Coord A exon
chr9:136910544-136913204
Coord C2 exon
chr9:136910415-136910543
Length
2661 bp
Sequences
Splice sites
5' ss Seq
AAAGTACGT
5' ss Score
7.99
3' ss Seq
CCTGTCACTGTGTGTTGCAGAGG
3' ss Score
8.89
Exon sequences
Seq C1 exon
AAAAAGGGCGTGAAGCGGAAAGCAGACACAACCACTCCCACGACGTCGGCCATCACTGCCAGCCGGAGTGAGTCGCCCCCGCCGTTGTCAGACCCCAAGCAGGCCAAAGTGGTGGCCCGGCGGGAGAGTGGTGGCCGCCCCATCAAGCCTCCCAAGAAGGACCTGGAGGACGGCGAGGTGCCCCAGCACGCAGGCAAGAAGGGCAAGCTGTCGGAGCACCTACGCTACTGCGACAGCATCCTCAGGGAGATGCTATCCAAGAAGCACGCGGCCTACGCCTGGCCCTTCTACAAGCCAGTGGATGCCGAGGCCCTGGAGCTGCACGACTACCACGACATCATCAAGCACCCGATGGACCTCAGCACCGTGAAA
Seq A exon
GTACGTGGCCGCGCGGCAGGCCCTGCTCTGCCCATGTCCTGCGGCTCTGCCGTGGGTGCTGATGTCTTGTGCCGGCTGAGTGGGGGCTGTCGGGGAGCAGGGTCTCGCTTGCCGGAGAAGCGCACCCTCCAGGCTGGCCCCCGCAGCGCCGGCTGTGGCTGGCAAGGCTCAGCGAGGAAGGCGTGCTCTGCCTGTGGGTCCCGGAGTCTGTGGCTCTGTTGTTGTTTATTCCCATCGAACCCGTTTAGTGATTTCATTGATTTCATTCCTACCTCCCATTCTGTATCATCAGGTCAGGGGGTCCCTAGAGCTGGGCCACTCTCACAGTTGGCAAAGTTTTAAAGCTGCACTTTGCTTCCCTCAAGCCCCGGATACAGGCGCCTCACAGCAGACAGGAGTGAGGCGGCCAGTGGGGATGGCCTGGCTTCTGTCCCCTAAGTGCCTCCAAGCCCCACCCCCTCACAAGACGGAAGCGGGACCTGGGTGGGTGGCAGAGCTGAGACCGAGAGCCTGGCCTCCCCCATGCCAGTCTTCTCAAGGCGGCAGCCTCTGCCTGGGCTCTTGTGTGCCTCACAGCAGGTCAGAGTGAGTCTGGTCCCTATGGGGGGTGGTGGTGGGTGCGGCATTTGAGCTGCACCGCCCCAAGCCAGGGTGAGCTCCACCGGGTCTTCCCTGAGCACCTTTCCAGACTCCTGGCTGGCACCTGCCCTCCCTCTGGGAGAGCTCCAAGCCAGCTCCCAGGGACGTGCAGGCAGTTGGCAGAGGTGTGACCTGCCTCCTCCGCCAACTGCCGTGCGGCCCTGGGAAGAGCTGCTGGCAGCCCTGTTGGGCAGTTGTTTTCATCCTGGGAAGCCAGTCGCAGTCATTCTGCCTACCTGAGGCAGGATCTGCTGATGAAACCCTTTTCTTCCTTGATTGACTGGATCTCGGGCAGGACAGACCTGGCTGGCCCAGGCCCCAGAGCCCGGTGCACAGTCAGGTGAAAGTGACGAGCGGGGCCGCCTGGCTCCACTGCCGTGGGTGGGGAAGCTGAGGGCCAGAGCCACGCAGCCCAGAAGCTGCCAGGAGCCTCGGCTGCAGCCTCCAGGGCTGGGGTTTGTGTGTCTCTACCATAGCACAGTTAACAGGAATTTCTGGAACATCATGGGGGGTTCCAGTGTTTGGGCTGGACTCAAGCTCAGCTTAATTCCATTTTGGTCAAAGGGTCTGATTTGCCCTTGAAACCATAATAAAGAAGCTCTAGAAAAACAATTCACTTTAAAGTCATGATCTGCTTTGTTCGGAGCTTCCCACCTCTATCTGTCCTGGCATGGCATGGGGAGAAGCCAGGTGCAGTGGCAGCACTTGCTGCCCGCGACTGTGGCCCGGACGCTGCGGAAAAGGGGCAGTGAATCAGGGAGAGAGGCCTCAGGACCTCTAGATTATACAGATGGAGCTTTTGGGGATGGTTTATCCCGGCACATGCTAAAACGGAAAACTAGCTTTTCCCCCAACATCAGAGGCTTCCAGGTCCCACTGTGCCCCCGGGTTCTTTCTGCCAGCCCTTCCTTCTGGATGGGTCTCATGTCTGAGTGCATAGGGTACGGGCCCTGAGTTGGGGGCGCCCTCTGCGGGTTAGGACCCGGCCCCTCCATCTCACTGGCACCTGGACAAATGCAGCCTGGACCCCACAGAGCGGTCGGGGTAGATTTGCCTTGCCCTTGCGTGTGTCGTCCCTCGAGGTCCCCGACAAGGTGCCTCTCCTTGAAGCCATCCCAGGATGGGAAACTCACTCCCTCGGGCACAGCGTGACCTCTCTTTGCCCCAACTAGTGTGTTCCCAGTGGCCACCTTGAAGCGTCCCTCGACGATCCTGCCTCTGGCCACTCCCTGGCAGAGCCACCTGCACCTCCCAGCTCTGGGGACTGACTGTGTGCCCCTCCTTACCCCTGCCGCCTGGCACTGTCTACCCAGGCCTTGGCCTCAGTTCTCTGCTTGCCAGAGCCAGGTGGGACCTGCGGTGGGTTTTGCTGTAGGGTCTCTGTGTGGCCGAGTAAACGTGGGTGGGTGTCAGCCGACACGCCCCCGTTGCCTCCACCCCTGTGGGGTTCAGGAGCTGCCGCTGGACACAGCGTGGAGTCCCTTAGGTCCAGCTAGGCCCCTGGGATACCAGGGTGCTTCTGTAAGACGCAAGCTGGCTAACAGCTACTGGCTTCCTCGAGGGAAAAAATTACATTTCCTTGTGTAGACTGAGCAGGCCCCCTGTTGTTGGTGGAGTCTGACTTTGCTGCAGCCTCACGCCCCCTGGGGCTGCTGATGGCGTGGCGGCGTGTGAAGATTTACCCGCTTTGTGTGAAGGGAAGCTCTGGACAAGGAAGGGGCCAAGGGACGCCTACGGGAACCTGGGATTTCTTGTTGAGTGCATTTTTCTTCCAATCAGGAGATCTGTCTCTGGAGTCCCAGACCCTCCCTGCCAAGCCATCAAGTCACCCTCTCATGTCCTCACTTTGGGTTTCCTCGTACGAGGTCCCAGAGAGCTGGGGTGTCCTGCCGGCCAGGCCAGTAGGCACTGCCCTGGAGCTGGCAGTGGCTCCTGAGGCTCCAGAGTTCATCTCGTGGGGTGTGGCAGAGAGTCCTGATGCCACGGGCCACGCTCACTGGCCCCTGTCACTGTGTGTTGCAG
Seq C2 exon
AGGAAGATGGATGGCCGAGAGTACCCAGACGCACAGGGCTTTGCTGCTGATGTCCGGCTGATGTTCTCGAATTGCTACAAATACAATCCCCCAGACCACGAGGTTGTGGCCATGGCCCGGAAGCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169925-BRD3:NM_007371:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.628 A=NA C2=0.256
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PU(52.8=37.9)
A:
NA
C2:
PF0043920=Bromodomain=PD(44.9=93.0),PF0093713=Corona_nucleoca=PU(5.1=16.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)