HsaINT0025096 @ hg19
Intron Retention
Gene
ENSG00000176919 | C8G
Description
complement component 8, gamma polypeptide [Source:HGNC Symbol;Acc:1354]
Coordinates
chr9:139840086-139840451:+
Coord C1 exon
chr9:139840086-139840222
Coord A exon
chr9:139840223-139840380
Coord C2 exon
chr9:139840381-139840451
Length
158 bp
Sequences
Splice sites
5' ss Seq
GCTGTGAGT
5' ss Score
7.39
3' ss Seq
CCTCCTCCCCGCCCCCCCAGGGA
3' ss Score
11.47
Exon sequences
Seq C1 exon
TTTGCAGGGACCTGGCTCCTTGTGGCTGTGGGCTCCGCTTGCCGTTTCCTGCAGGAGCAGGGCCACCGGGCCGAGGCCACCACACTGCATGTGGCTCCCCAGGGCACAGCCATGGCTGTCAGTACCTTCCGAAAGCT
Seq A exon
GTGAGTCCCAGAGCAGCCCTGCACCCTAACCCCAACCCTCCTCTCAGCCCCCGGACTTCAGCCCTGCTCTGGCCCCTGACCCCACCCCGGCTGTGGCCTGGACTAGGATTCCTGGTTGGGGTCTCCCAGCCTGTGGTGCCTCCTCCCCGCCCCCCCAG
Seq C2 exon
GGATGGGATCTGCTGGCAGGTGCGCCAGCTCTATGGAGACACAGGGGTCCTCGGCCGCTTCCTGCTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176919-C8G:NM_000606:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006118=Lipocalin=PU(31.7=95.7)
A:
NA
C2:
PF0006118=Lipocalin=FE(17.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGGACCTGGCTCCTTGTG
R:
CAGGAAGCGGCCGAGGAC
Band lengths:
196-354
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)