HsaEX0011507 @ hg19
Exon Skipping
Gene
ENSG00000176919 | C8G
Description
complement component 8, gamma polypeptide [Source:HGNC Symbol;Acc:1354]
Coordinates
chr9:139840086-139840644:+
Coord C1 exon
chr9:139840086-139840222
Coord A exon
chr9:139840381-139840451
Coord C2 exon
chr9:139840537-139840644
Length
71 bp
Sequences
Splice sites
3' ss Seq
CCTCCTCCCCGCCCCCCCAGGGA
3' ss Score
11.47
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
TTTGCAGGGACCTGGCTCCTTGTGGCTGTGGGCTCCGCTTGCCGTTTCCTGCAGGAGCAGGGCCACCGGGCCGAGGCCACCACACTGCATGTGGCTCCCCAGGGCACAGCCATGGCTGTCAGTACCTTCCGAAAGCT
Seq A exon
GGATGGGATCTGCTGGCAGGTGCGCCAGCTCTATGGAGACACAGGGGTCCTCGGCCGCTTCCTGCTTCAAG
Seq C2 exon
CCCGAGACGCCCGAGGGGCTGTGCACGTGGTTGTCGCTGAGACCGACTACCAGAGTTTCGCTGTCCTGTACCTGGAGCGGGCGGGGCAGCTGTCAGTGAAGCTCTACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176919_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.065 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006118=Lipocalin=PU(31.7=95.7)
A:
PF0006118=Lipocalin=FE(17.3=100)
C2:
PF0006118=Lipocalin=FE(25.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGCCGTTTCCTGCAGGAG
R:
CCAGGTACAGGACAGCGAAAC
Band lengths:
175-246
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)