HsaINT0026575 @ hg19
Intron Retention
Gene
ENSG00000167535 | CACNB3
Description
calcium channel, voltage-dependent, beta 3 subunit [Source:HGNC Symbol;Acc:1403]
Coordinates
chr12:49212512-49217249:+
Coord C1 exon
chr12:49212512-49212757
Coord A exon
chr12:49212758-49217126
Coord C2 exon
chr12:49217127-49217249
Length
4369 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
3' ss Seq
CAGCCTCTTTCCCAACCCAGGGT
3' ss Score
6.21
Exon sequences
Seq C1 exon
GGGTGGGGGGAGCGGTGATCTGAGCTCCGAGCAGCTGGTCTTCGCGGCTCGCTCCCTCCTTCGCGCTCTCTCGCTCCCTGCCGCCGCCCGCAGGGCTGCGGGGCTCGGTGGCATCTCCCGGGCGCGGCCCGCAGTCCTTGCCCCTGCCTCCGGGCCGCTCCCGCCCCCGGCGCCGCTCGCTCCCCCGACCCGGACTCCCCCATGTATGACGACTCCTACGTGCCCGGGTTTGAGGACTCGGAGGCG
Seq A exon
GTGAGTGCCCACGATGAGGGTGGGGGCGGGGAAGTTGGGGTGACACCTCCTCTCCCTTCAACCCTTTCCCCGGTTCAGGACTTTGAAAAACGCCTCAGTGGCAGGGCAGGGTTTGTAGGGGGGCGCTCTAAGAACGTGGGGAGATGGATTTTCATGCCAAGCGTTCCCCAGCGACCCAGACTCAGACCCTGGGGCATCGGGTGTGTGCAGAGAGGGGGCAGTATAGGGGAAGGGCTCAAGCAGGTGGCTCCACGGCCCAGGAAAGAGGGGTGGGAGAAGGCAGGGCTGGAGGCCGAGGGCACAGAGGCTCTGGAGAGGGAACACGCCATGTCTGGAGTTCCAAATTCTGGATTTCTGGGGTCTGAACACAACAGCTAGGAGAGCCGCCGAGGTGGTTGGGGAGGCAGACATTCTAGACCTCTTGTGCCTCAAGCAAACGACACATCAGGGAGCTGAGAGGACATCAGGGAGCCAGGGGCCAACCTCTTCAGACAGACGGATCCTAAAACTTGAGGAGCTCCATTATTCCCTTCCACCCCCTCCATCTCTGCGCATTGCCTCATCTCCTCACCCTTTCTCTAGCCCAGTTTCTCTCCCAGGCTGAAACCTGGGCGCCCAGCACATGGGTAGGCCAGGTGACTGAGCCCCATCTATTCCACAGCCCCCTGCTGAGGCTTCCTCTGCAGCGGGCATCCTGAGCTCTTGCCCAGCATGGAGGGCCTGGAGGTGAGGCCAGAGGAGCTGAGGGCCTGGGGATGGAGAGGAAGCGCTTTGCTCAGAGAAACAGGCAACCGATAAATATTTAATTCTCCTCTTTGCTTTTATCTCCTGACCCACTGAGACAAATCAGCTCATTAAGCAGTGATTCCCGGAGCTCAGACAGCAGGGAGAGTGCCTGGAAAGATGGGGCAAGAATGCGGAGCAGCTTCTCAGCCCCTTGGAGCTGACAACTTTCCCTCAAATGTCCTGTAAGAAGGCCTCCTTAGGAGTGGACCACTAGATGGCTTGGAAGGGGCCCCAATAGGTTGGAGCACCCCTGGGTCGGAAAGAGGAGTTCATGTTCAAGTCTTCTCCCATCACTTACTGCCAGGCCCAGGATAGATGAATGCTGATGTTCAGAATAGGCAACTGTCCTTTTCTGGGACTGGTCTCCTTCTGGGCCCAATTCTCCATGGGGCCTCTGGGGCTAATTACATTGCCGCTAGATCAGATCATTTTCAAGGCTCTGGTGGACACCTCTTTCTGACAGTTGAAGGGACAGCTGGTATAGCCCAGGGTGCCAAGGTGAGCTTGAAAACAAACCTCTCTGTGGGGCTGGATGGCCCTAGGAGGTTCTTCCCATCCCTGGTGAGAAGGCAAGGGCTATTGCAAGGAGCAGACTGACATGTGGATGGTGTTGGAGGGCAGCCTGCTGACCCATTGCTCCCTCCCATCTCTCTCTGGCTCTGATCACCCTCCCCCACTTCCCTTTCTCTTGCCTGGCTCCTTGCTCTCCCTGAGGCCCCCTCTGAAGCAGTAGGAGGGAGATCAGGCTCTAAATAAATCCAACGGCTCATCTCCCTCCTCTCCTTCCCCCGTGCCAGGCAAGAGAGGAGCTGCAGCCTGCCCACACACTCACTAGGCAAGGGGGGCACCACCAGGGCACTGTGCCAACTCCTGGCAGCTCCAAAGTACTGAAACTCTGGCTATTTTGGCGTAGCAGGGTACAGGAAAGGTAAGACCCTAGATCATGCTTGGCAGGGCAGCCCTGGCCTCCCCAAGTAATACTGGAGCACTAGAGATGAGTGAGCCTGGAGGACTTGGGAGTAATGGAGAGGGGGTTCCATTCTGAGCACAACTCATTAAATATTTAGGAAGAGATCCTGTGATTCCCATCCCAGGGTGAGAGGTCAGGTAAGCCAGATGCCTCAGGCGTTATGATTACTAAATTAGGCCGCCAGCGGTGCCTCACACCTGTAATCCCAGCACTTTGGGTGGCCGAGGTAGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAATATGGTGAAACCCTGTGTCTACTAAAAATATAAAAATTAGCCCAGCATGGTGGCACATGCCTGTAGTCCCAACTACTCAGGAGGCTGGGGCAGTAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGACATCGCACCATTACATTCCAGCCTGGGCATCACAGTGAAACTCCATCTCAAAAAAAAAAAAAAAATTACTAAATTAAACCAGGCATAGAGACTCATGCCTATAATCCCAATGCTTTGGGAGGCTAAGGTAGGAAGATGGCTTAAGCCCAGGAGTTTGAGACCAGCCTAGGCAACATAGCAAGATCCTGTCTCTACAAAAAACTAGTAGGCATGGTAGCGCATGCCTGTAGTCGTAGCTACTCAGGAGACAGGAGGATCGCTTGAGCCCAGGAGTTCAAGCCTGCAGTGAGCTACGATTGTGCCACTACACTCCAGCCTGGGTGACAGAGCAAGACCTGTCTCTAAGTAAATAAATAAAATAATAAAAATAAAGATTACTAAATTGGGCTGAGAGCCTGGAGCACAGGCAGAAAAGGTCAGACTCCTCTTTTAGCACAGTTCTGGGCCTCTGGGAGGTACCCAATGTATCTGTACCAAAGCGAGTGGTCATCTGCCTTGCCTCCTGCCTCCCAGTCTGTTGGCCCCTGTCTGGTTGCTTCAGACACCAACATCCCACAGAGGTTTCTCTTGTGTCCTAAGACCCCTGGGAAGGAGGTCCCTCACCCTGTGCAAAGATTATTTCTGGGGTTCATCCCCCACTTATCCTGCTGCCATCCAGCCTCATTTTGTTCTCAGGAGAGATGAGGAACAGTCGGCGGACTACTCTTCTGTAAAATGAAAGATCTTTCCCCCTTGTGCTATCTTCAGGCCTTTGGTCTACTATAGACACTGTCTTTAGCCTAAGGCTCGAGAGCCTGGGCTGACCCCTAGCTGAACAGCCCTCTTGCCCACGGCAGGGTAGGGGTAGAGGGCATGGTTGACAGCAGGTATGTGATTTTGCCTTCTTCTCTGAGAGTCTGGCCTCTGCTGCCTTCCGTAGGTGGTCATGCCCAGTGAGCTTGAGAGAATGTTCCTCTACCTGAGGACATTCTAAAGCCCCTTCCCCTATACACACACACACTCCTGCATGAACCCCTTATCTAGGCTTATCCCTTCTCTCTGCCACTGGCATCTCAGAATTGTGGGAAGTATCACTTGAGGCTTCTCCCCACAGAGAGGGAAAACTGAGGCAGGAAACGAAAGACTCCCTTTCCCTGACAGAGGAGGAAACCCAGACATTGTAACCTCTGGGCTCTTGTCTCAAAGTCCAGCGTCCCTTACTCATTTGTGCCTCTCCCTCATGGTCTTGAGGCTGAACTCTGTGACCGTCAAATGCACCCTCATTGCCCAAGACCTTTCCTATGGGCAGGACTCAGAGACTCTCCTTGCTCATGTTACCCCCTCCCCACATCCCCGGGGTCCTGCTCCGTAGCTAGGTTGCCTGGCACTAGCATAGCCTTCTTCTAGGGCTGATGTCCCCTGGGCCTGGGAAAGGACTAGGGAGATGTAGGCCAAGTGGTAGGTGTGGCCCAGCCTCACCTGCACCCAGGGAGACAGCTTTGTGTTCTTGGTCTGTGTCTTGTTTGCTGCCCACACCTGGCTAGTTGCCCCAGCAGGTGTGGAAGGAAGAAAAGTAGGGGGTGGGGAGAGCAAAGGGGAGGTAACTTCTAGGAGCTGGCAGCTTTGTGTCCTCCTCTTCACCCTGGAAGGGTAAGGGCTCACCATTTGGGAGCCTTCAGAGCCTTGTTGGAGTAGGGAAAGTGGAATCTTAGGGGGCAGATGGCTGGATCCCCACATTCAGGACTGGTGCTGTGCCAACCAGCATCTCTTGACTGTTGCGGCTGGCTGGACTCCTGACAGGCATCTTAAAGGGATGATGTCCAGGCTGCTTTGCAGGCTGCTATGAACAAGAGGGCTGGGTCTCCTGGATCCAGAATCATCTCTAATACATCATCTTCAGCACACCTCCCTTCCCTCGGCTCAGAGGACATGTTAGAGGGGAGAAAAGGGAGGAAAGAGAGAAGTGAAGGCTCTATTCAAAGCTGCAGTATTAATAGGCTTGGGGGAGGAGGGGCCCAGATCTTTGCACCTATGGATTGGGCCAGCTTTCCTGTAGCCTCAGAGGCACTGGGGCCCTTCTCAGGGGATAGGAGGGGCCATAGGGACCCAGCTATCCCCTTGGAGATGGAGAAACTGGGGGCAATAGAGGCAACACTGTAAGGTGAGGAGGGTGCCTCCATGGCATCCTTCATGCCGGAGCCTGGGAGTCACAGCCTCTTTCCCAACCCAG
Seq C2 exon
GGTTCAGCCGACTCCTACACCAGCCGCCCATCTCTGGACTCAGACGTCTCCCTGGAGGAGGACCGGGAGAGTGCCCGGCGTGAAGTAGAGAGCCAGGCTCAGCAGCAGCTCGAAAGGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167535-CACNB3:NM_000725:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=NA C2=0.976
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF120523=VGCC_beta4Aa_N=PU(93.0=97.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)