HsaINT0026575 @ hg38
Intron Retention
Gene
ENSG00000167535 | CACNB3
Description
calcium voltage-gated channel auxiliary subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1403]
Coordinates
chr12:48818731-48823466:+
Coord C1 exon
chr12:48818731-48818974
Coord A exon
chr12:48818975-48823343
Coord C2 exon
chr12:48823344-48823466
Length
4369 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
3' ss Seq
CAGCCTCTTTCCCAACCCAGGGT
3' ss Score
6.21
Exon sequences
Seq C1 exon
GTGGGGGGAGCGGTGATCTGAGCTCCGAGCAGCTGGTCTTCGCGGCTCGCTCCCTCCTTCGCGCTCTCTCGCTCCCTGCCGCCGCCCGCAGGGCTGCGGGGCTCGGTGGCATCTCCCGGGCGCGGCCCGCAGTCCTTGCCCCTGCCTCCGGGCCGCTCCCGCCCCCGGCGCCGCTCGCTCCCCCGACCCGGACTCCCCCATGTATGACGACTCCTACGTGCCCGGGTTTGAGGACTCGGAGGCG
Seq A exon
GTGAGTGCCCACGATGAGGGTGGGGGCGGGGAAGTTGGGGTGACACCTCCTCTCCCTTCAACCCTTTCCCCGGTTCAGGACTTTGAAAAACGCCTCAGTGGCAGGGCAGGGTTTGTAGGGGGGCGCTCTAAGAACGTGGGGAGATGGATTTTCATGCCAAGCGTTCCCCAGCGACCCAGACTCAGACCCTGGGGCATCGGGTGTGTGCAGAGAGGGGGCAGTATAGGGGAAGGGCTCAAGCAGGTGGCTCCACGGCCCAGGAAAGAGGGGTGGGAGAAGGCAGGGCTGGAGGCCGAGGGCACAGAGGCTCTGGAGAGGGAACACGCCATGTCTGGAGTTCCAAATTCTGGATTTCTGGGGTCTGAACACAACAGCTAGGAGAGCCGCCGAGGTGGTTGGGGAGGCAGACATTCTAGACCTCTTGTGCCTCAAGCAAACGACACATCAGGGAGCTGAGAGGACATCAGGGAGCCAGGGGCCAACCTCTTCAGACAGACGGATCCTAAAACTTGAGGAGCTCCATTATTCCCTTCCACCCCCTCCATCTCTGCGCATTGCCTCATCTCCTCACCCTTTCTCTAGCCCAGTTTCTCTCCCAGGCTGAAACCTGGGCGCCCAGCACATGGGTAGGCCAGGTGACTGAGCCCCATCTATTCCACAGCCCCCTGCTGAGGCTTCCTCTGCAGCGGGCATCCTGAGCTCTTGCCCAGCATGGAGGGCCTGGAGGTGAGGCCAGAGGAGCTGAGGGCCTGGGGATGGAGAGGAAGCGCTTTGCTCAGAGAAACAGGCAACCGATAAATATTTAATTCTCCTCTTTGCTTTTATCTCCTGACCCACTGAGACAAATCAGCTCATTAAGCAGTGATTCCCGGAGCTCAGACAGCAGGGAGAGTGCCTGGAAAGATGGGGCAAGAATGCGGAGCAGCTTCTCAGCCCCTTGGAGCTGACAACTTTCCCTCAAATGTCCTGTAAGAAGGCCTCCTTAGGAGTGGACCACTAGATGGCTTGGAAGGGGCCCCAATAGGTTGGAGCACCCCTGGGTCGGAAAGAGGAGTTCATGTTCAAGTCTTCTCCCATCACTTACTGCCAGGCCCAGGATAGATGAATGCTGATGTTCAGAATAGGCAACTGTCCTTTTCTGGGACTGGTCTCCTTCTGGGCCCAATTCTCCATGGGGCCTCTGGGGCTAATTACATTGCCGCTAGATCAGATCATTTTCAAGGCTCTGGTGGACACCTCTTTCTGACAGTTGAAGGGACAGCTGGTATAGCCCAGGGTGCCAAGGTGAGCTTGAAAACAAACCTCTCTGTGGGGCTGGATGGCCCTAGGAGGTTCTTCCCATCCCTGGTGAGAAGGCAAGGGCTATTGCAAGGAGCAGACTGACATGTGGATGGTGTTGGAGGGCAGCCTGCTGACCCATTGCTCCCTCCCATCTCTCTCTGGCTCTGATCACCCTCCCCCACTTCCCTTTCTCTTGCCTGGCTCCTTGCTCTCCCTGAGGCCCCCTCTGAAGCAGTAGGAGGGAGATCAGGCTCTAAATAAATCCAACGGCTCATCTCCCTCCTCTCCTTCCCCCGTGCCAGGCAAGAGAGGAGCTGCAGCCTGCCCACACACTCACTAGGCAAGGGGGGCACCACCAGGGCACTGTGCCAACTCCTGGCAGCTCCAAAGTACTGAAACTCTGGCTATTTTGGCGTAGCAGGGTACAGGAAAGGTAAGACCCTAGATCATGCTTGGCAGGGCAGCCCTGGCCTCCCCAAGTAATACTGGAGCACTAGAGATGAGTGAGCCTGGAGGACTTGGGAGTAATGGAGAGGGGGTTCCATTCTGAGCACAACTCATTAAATATTTAGGAAGAGATCCTGTGATTCCCATCCCAGGGTGAGAGGTCAGGTAAGCCAGATGCCTCAGGCGTTATGATTACTAAATTAGGCCGCCAGCGGTGCCTCACACCTGTAATCCCAGCACTTTGGGTGGCCGAGGTAGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAATATGGTGAAACCCTGTGTCTACTAAAAATATAAAAATTAGCCCAGCATGGTGGCACATGCCTGTAGTCCCAACTACTCAGGAGGCTGGGGCAGTAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGACATCGCACCATTACATTCCAGCCTGGGCATCACAGTGAAACTCCATCTCAAAAAAAAAAAAAAAATTACTAAATTAAACCAGGCATAGAGACTCATGCCTATAATCCCAATGCTTTGGGAGGCTAAGGTAGGAAGATGGCTTAAGCCCAGGAGTTTGAGACCAGCCTAGGCAACATAGCAAGATCCTGTCTCTACAAAAAACTAGTAGGCATGGTAGCGCATGCCTGTAGTCGTAGCTACTCAGGAGACAGGAGGATCGCTTGAGCCCAGGAGTTCAAGCCTGCAGTGAGCTACGATTGTGCCACTACACTCCAGCCTGGGTGACAGAGCAAGACCTGTCTCTAAGTAAATAAATAAAATAATAAAAATAAAGATTACTAAATTGGGCTGAGAGCCTGGAGCACAGGCAGAAAAGGTCAGACTCCTCTTTTAGCACAGTTCTGGGCCTCTGGGAGGTACCCAATGTATCTGTACCAAAGCGAGTGGTCATCTGCCTTGCCTCCTGCCTCCCAGTCTGTTGGCCCCTGTCTGGTTGCTTCAGACACCAACATCCCACAGAGGTTTCTCTTGTGTCCTAAGACCCCTGGGAAGGAGGTCCCTCACCCTGTGCAAAGATTATTTCTGGGGTTCATCCCCCACTTATCCTGCTGCCATCCAGCCTCATTTTGTTCTCAGGAGAGATGAGGAACAGTCGGCGGACTACTCTTCTGTAAAATGAAAGATCTTTCCCCCTTGTGCTATCTTCAGGCCTTTGGTCTACTATAGACACTGTCTTTAGCCTAAGGCTCGAGAGCCTGGGCTGACCCCTAGCTGAACAGCCCTCTTGCCCACGGCAGGGTAGGGGTAGAGGGCATGGTTGACAGCAGGTATGTGATTTTGCCTTCTTCTCTGAGAGTCTGGCCTCTGCTGCCTTCCGTAGGTGGTCATGCCCAGTGAGCTTGAGAGAATGTTCCTCTACCTGAGGACATTCTAAAGCCCCTTCCCCTATACACACACACACTCCTGCATGAACCCCTTATCTAGGCTTATCCCTTCTCTCTGCCACTGGCATCTCAGAATTGTGGGAAGTATCACTTGAGGCTTCTCCCCACAGAGAGGGAAAACTGAGGCAGGAAACGAAAGACTCCCTTTCCCTGACAGAGGAGGAAACCCAGACATTGTAACCTCTGGGCTCTTGTCTCAAAGTCCAGCGTCCCTTACTCATTTGTGCCTCTCCCTCATGGTCTTGAGGCTGAACTCTGTGACCGTCAAATGCACCCTCATTGCCCAAGACCTTTCCTATGGGCAGGACTCAGAGACTCTCCTTGCTCATGTTACCCCCTCCCCACATCCCCGGGGTCCTGCTCCGTAGCTAGGTTGCCTGGCACTAGCATAGCCTTCTTCTAGGGCTGATGTCCCCTGGGCCTGGGAAAGGACTAGGGAGATGTAGGCCAAGTGGTAGGTGTGGCCCAGCCTCACCTGCACCCAGGGAGACAGCTTTGTGTTCTTGGTCTGTGTCTTGTTTGCTGCCCACACCTGGCTAGTTGCCCCAGCAGGTGTGGAAGGAAGAAAAGTAGGGGGTGGGGAGAGCAAAGGGGAGGTAACTTCTAGGAGCTGGCAGCTTTGTGTCCTCCTCTTCACCCTGGAAGGGTAAGGGCTCACCATTTGGGAGCCTTCAGAGCCTTGTTGGAGTAGGGAAAGTGGAATCTTAGGGGGCAGATGGCTGGATCCCCACATTCAGGACTGGTGCTGTGCCAACCAGCATCTCTTGACTGTTGCGGCTGGCTGGACTCCTGACAGGCATCTTAAAGGGATGATGTCCAGGCTGCTTTGCAGGCTGCTATGAACAAGAGGGCTGGGTCTCCTGGATCCAGAATCATCTCTAATACATCATCTTCAGCACACCTCCCTTCCCTCGGCTCAGAGGACATGTTAGAGGGGAGAAAAGGGAGGAAAGAGAGAAGTGAAGGCTCTATTCAAAGCTGCAGTATTAATAGGCTTGGGGGAGGAGGGGCCCAGATCTTTGCACCTATGGATTGGGCCAGCTTTCCTGTAGCCTCAGAGGCACTGGGGCCCTTCTCAGGGGATAGGAGGGGCCATAGGGACCCAGCTATCCCCTTGGAGATGGAGAAACTGGGGGCAATAGAGGCAACACTGTAAGGTGAGGAGGGTGCCTCCATGGCATCCTTCATGCCGGAGCCTGGGAGTCACAGCCTCTTTCCCAACCCAG
Seq C2 exon
GGTTCAGCCGACTCCTACACCAGCCGCCCATCTCTGGACTCAGACGTCTCCCTGGAGGAGGACCGGGAGAGTGCCCGGCGTGAAGTAGAGAGCCAGGCTCAGCAGCAGCTCGAAAGGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167535:ENST00000301050:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.478 A=NA C2=0.920
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF120523=VGCC_beta4Aa_N=PU(93.0=97.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development