HsaINT0029141 @ hg19
Intron Retention
Gene
ENSG00000135205 | CCDC146
Description
coiled-coil domain containing 146 [Source:HGNC Symbol;Acc:29296]
Coordinates
chr7:76866264-76871217:+
Coord C1 exon
chr7:76866264-76866346
Coord A exon
chr7:76866347-76871007
Coord C2 exon
chr7:76871008-76871217
Length
4661 bp
Sequences
Splice sites
5' ss Seq
GAGGTATGC
5' ss Score
9.12
3' ss Seq
CTGTTTTTCATGTAACCCAGCAC
3' ss Score
4.05
Exon sequences
Seq C1 exon
TTACATGCTATGGGAAAACTTCCTGGAACCAGAATGGCAGCGTTAAAAGCCAAGTATACCTTGCTGCATGACGCCGTGATGAG
Seq A exon
GTATGCAATTTACCAATATGGAGACATGATTAATCACCTTTAAATTTCTTACTGGTGATGAGACCTGTCTTCATTTGCATTCCCCCATAAGCAGACCCTGAGGCAAGGATTTGCGTTCAGGGAGTTTGAGAAGTGGTACGAGAAAGCATCGTGAGAGAGTGGGGAAGTGCGACTGGGAAGGAAGGAATCTAGCCTTGATCAGGCCGTGTACATCTGCGAGTTTATATGATGGGCTACTGGGGCTCAGCCTCACAGAGGAGCCTCTGAGTGGCTCACCTCAGCACTCTCCCACTGAAGAGTGAGGAAACTGGAATATTTGCCCACCAGTTTCCACCACTCATTTATTACAAATTACTTCCAGGGAGATTAGCTCTTGGCACTTCCAGCTTGCGCTTTGACAAACCAAGCAAACTTTGATGGCCAGAGACAGCTCTCAGGCGGAGGGACACAGGTGCTGCTGATACATATGGTAACTGTCCACTAAAGCTGCAGGTGGGCAAAAGGATTCTGGTGGGACACTGACAGTCTCTGCATAGGACACACCTGCAGGACTCTTCTCCCGTGTCTGTTCATCACTCAGAGGTGTAGATTCTCCAACAACCCCAGCTTGAGTCTGCTGAGACCCTGTCTGTACTTCTCACCTCCTCCCCATATCACAAGCTACTTACACCTTGCAAGTCCCAATCACCAACAGGTCAGAAGAACAGGCTATCATAGAAGAGTCCAGCAAGCCTGCCTGAGCACTGGCTATTAGCCACTGGGAATTAAGAGGGCAGGGGAGTGAAGAAAGAGGGAAAACCCTAATGTGCTGTGATTCTTTACCACTCCCAAGCCTCTTTCTTTCCTTCCCCCACCTCTTGTCTCAGGGCCTTGCATTGTATCTTCATCAAAAGCCAAGGAGCAACAGCAACAGATAGAAACTCCATGCTGCCACTCCCCAGCCATCCTCTCCCCGCAATTCCCAATCACTTCCCCTCCTTCTTATCTTGCCCAGAGATATTTGGCTACTTTGAGGGTAAAAGCATGAGGGAAGAGTGAACAACTTGGAAAAGAGCAGAGCTGCATTCCTATGCAAACTTCAAGTGCACCCAGGTTCCTCACACCCCTCCAAAGCCCCCAGCCTTGGTTCCTCATCCTCAAGCCCAAGCCAAGTCCTCACCCCCACACCTAATGGAGGTTCCATTCCCCCGTAGCTGGTCACGCCTGCCAGTGTGTTCTCAGAGTTCTCAAGGCTCAGGAATTTTGAGACTTTAAGTGGAAAGTCTGGAGTAATCTTTTACAACATACTTCACACTGCTTAACTGAGAGGAAATGCCATGCAGTTCTCTGGGCATCCCTCCAATCCTCTTTGCAGATACAAGGAATATCAGTGTTTCCTGCCCTCTGGATAGCTCTTCTTTTTTTTTAGACAGAGTCTCCCTCTGTCACCCAGGCTGGAGTGCAGTGGCCTGGTCTTGGCTCACTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGACTCTTGAGTAGCTAGGACTACAGGAGCCCGCCACCACACCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACTGGGTTAGCCAGGATGGTCTCAATCTCCTGACCTTGTGATCCTCACGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCTGGATAGCTCTTATCTAGAGCCCAGTGGAGATTTGCAGGGTGCTTTGACTTAACTTCCTCCTCCCCTGGCCCACAACTCAGTTCCCTGGCCCCTAATGACAAGTAGCAATGCAGGACCTCAGCTATGGCACTATTTCTTCCTCTTCCAGGTTGTGTTGCAAAACAGTTAACTTCCCTTCTGCTACCCACATTTTACATCTTGACCACTTAGTTCCCTCTAATGCCATTGCAAATACTCACCATTCTCTCCTACTCCCAATGCCTGATGGGTGGGAAAAACATGAAGTAGACTCTTCATTCGTGCTGCTAGGACTACAGCTGGGCAGATATAGCCTGGAAATATTGAACTGAAACTGAATGAGTCTTCCATAGAAACCATGTTATAAGAGTTGTTAAAGTCTCTTCTACTGGTATCATGTTTTAAATACATGTGGGTAAGTTGCGATTTGTGTTCTGGCTGGAACCCTACCACCCTGTCCTTTCTATGCAAAAACAGGCACTGTAGCCTGGTCCAACAGCTTACAATTTCAATAGCTGAAGCCTGACCTATTAAGGAGACCAGATAACTTTAGATTTACAAAGTTTATTAGCATACATGAAAATTGAATTATAGGAGAATAATTCCAGCTTTCATTAATGAAAATTATTTGAGGTATCACTGTAGCTATTGTTGTTGCTATTTGGTACCTAACATCATGCCTGGAACGTGTTATGTCCCAGTAAATGTTTTGCTAGATGCTATTGAGCAAATGACATTATAAAACCTGGGAAAATGGATGTATCTGTACTGAATTGAGAATATCACAAAGGTGAGGCAGACACAAGGTAACTTCAGTTGAGATTGGCTTGATCAAGTCATTGGGCGTCTCTGCAAATGAGCTGGAACTTGAAGATTTATCTTGGTGAGGACAGTTGGTGGGGAGCATACATCAAAAGAGAGCTCTGGCTCTAAAACAGGAAGTGGTGAGGGCTTACTTCAAATAGGAGAGGTAGCTAATATAAGGGTTTCTGGGAAAGAGGAATCATATCTACTGGTAAGGTTGGAGCCGATGCTTGCTGATGCTAGCTTGCAGCATAGAGGAGTTCTATAAGATACTGGAGATTCCGCCATGTCCTTTTTCTACATCCTCTGACAGATGTTTAGTCCTTTTCCCTACATAGGGCCAAGGTCATAGAATATAACTGGGGTTGTAGGAATCTCCCTCTACCGTGACCTTCAAGTCCATCCAGCTCTAACCAGTGTCCAATTTAGAATCAGAAATCTGTAAATTTATTTATATTCATAATTGCGTATGGGAATTTCTCTTCCTAGTTTCCTAATAAAGTGCCATTAGAAAAGTTTCTGTTTTTTCATAGTTCACTAAGTGGGGAGAGATTTTCCTACAATTATGTTACAAGAATTCAAGAGAGCTAGGGTTGTTTGGGGAGTTCAAGGGAAAACCTCCTCTTTCCGTATCATTTATCCCCTTCTAGTAAGTCATAATCATTCTTCAAAGTCAAGTTCAAATGTCACATTCCCATTGAGTGATCCTTTCTCTGTTGTCTCCTGCTGTCTTGATCTGGACACCAGCGGTAGTACTTGTCATCTGGTATTCCTCCGCATCTGCCAGATTGTAAGATTCTTGAAGCTAGGAGCTAAGCCTTATTCACCTCTTGCACCTAGCATAGTACAGTCATCTCTTGGTATCCTTGGGGGATTGATTCCAGGACCTCCTGCAGATACCAAAATCCATGGATACTCCAGTCCCTGATATAAAATGGTATAGTATTTGCATGTAACTTAATCACATCCTCCTGTATACTTTAAATCATTTCTAGATTACTTGTGATACCTAATACAATATAAATGCTATGTAAATGGTTGTTATGCTGTATTGTTTAGGCAATCATGACAAGAAAAGTCTGTACATGTTCAGTAAATAAACAATTTTTAAGTAAACATTTTATTTTGGAATAATTTTAGATTCATAGAAAAGTTGCAAAAATAATATACGAAGTTCCCGTCTATCCTTCACCCATTTTCCTCTAATGGGAGCATCTTACATAACCATGGTCCATCAAAACTAGGAAGTTAACATTCGTATATTACTATTAATTAAACTTCAGATTTTCAACAGTTTTTCCACTAATGCTCTTTTTTTTGTTCCAGGACCCAATGCAGTATACCCCACTATATTTAGCCCTCATCTCTCCTTGATCTCTGTGACAATTTCTCAGTCTTTCCTTGTTTTTTTTAAATCACGTTGACATTTTTTGTTTTTTTTTGTTTGTTTGTTTGTTTGTTTTTTTGGGTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCGCCCAGGCGGGAGTGCAGTGGCTCAATCTCGGCTGAGATGGAGTCTCACTCTGTCGCCCAGGCGGGAGTGCAGTGGCTCAATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGAACGGTTTCGATCTCCTGACCTTGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCATCGCGCCCGGCCACGTTGACAGTTTTAAGAGTGCCAGTCAGGTATTCTATAGAGCATTTCTCAGTTTGGAATTTTTCTCATATTTAGGCCAGAGTTAGGTGTTTTGGAGGAGAATACCACAAAGGTGAAGCAGACTCAATTTTTTAACAAAAATTTTCCCTCGTGGTTGGTTGAATCCACAGATGTGGACTCACGGACATGAAGGGTCAACTGACTTGGCACAAAAATGTCCCAGAGTTGAGTTGATCTGAGGAGTGGGGAGCAGCTATCCTCACTAGACCCCCACAGGAGCCACCGAGGATGTACATGTCTCATTATGTGAGTCTCTGTTTTTCATGTAACCCAG
Seq C2 exon
CACACAAGAGTCAGAGGTCCAACTGCTACAGAATGCCAAACGTTTCACTGAGCAAATACAACAGCAGCAGTTTCACCTGCAGCAAGCTGATAATTTTCCAGAAGCATTCTCCACGGAGGTCTCCAAAATGAGAGAACAACTTCTCAAGTATCAAAATGAATATAATGCAGTGAAGGAAAGAGAGTTCCATAATCAGTACAGATTAAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135205-CCDC146:NM_020879:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.021
Domain overlap (PFAM):
C1:
PF0226314=GBP=PU(14.0=50.0),PF039618=DUF342=FE(19.9=100)
A:
NA
C2:
PF0226314=GBP=FE(70.0=100),PF039618=DUF342=FE(51.5=100),PF129382=M_domain=PU(77.1=90.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)