HsaEX0013061 @ hg19
Exon Skipping
Gene
ENSG00000135205 | CCDC146
Description
coiled-coil domain containing 146 [Source:HGNC Symbol;Acc:29296]
Coordinates
chr7:76796975-76871217:+
Coord C1 exon
chr7:76796975-76797141
Coord A exon
chr7:76866264-76866346
Coord C2 exon
chr7:76871008-76871217
Length
83 bp
Sequences
Splice sites
3' ss Seq
CCTTATGTTCTCTTTGCTAGTTA
3' ss Score
8.1
5' ss Seq
GAGGTATGC
5' ss Score
9.12
Exon sequences
Seq C1 exon
AATCGTGAAAAATGGAAGACAGTAGCACAGACACAGAAAAAGAAGAGGAAGAGGAGAAAGATGAAAAGGATCAAGAGCCCATTTATGCCATAGTGCCCACAATTAACATTCAAGATGAGCGGTTTGTTGATTTATCTGAAACTCCAGCTTTCATTTTTCTGCATGAG
Seq A exon
TTACATGCTATGGGAAAACTTCCTGGAACCAGAATGGCAGCGTTAAAAGCCAAGTATACCTTGCTGCATGACGCCGTGATGAG
Seq C2 exon
CACACAAGAGTCAGAGGTCCAACTGCTACAGAATGCCAAACGTTTCACTGAGCAAATACAACAGCAGCAGTTTCACCTGCAGCAAGCTGATAATTTTCCAGAAGCATTCTCCACGGAGGTCTCCAAAATGAGAGAACAACTTCTCAAGTATCAAAATGAATATAATGCAGTGAAGGAAAGAGAGTTCCATAATCAGTACAGATTAAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135205-'4-7,'4-6,6-7
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.519 A=0.000 C2=0.021
Domain overlap (PFAM):
C1:
PF039618=DUF342=PU(14.7=38.5)
A:
PF0226314=GBP=PU(14.0=50.0),PF039618=DUF342=FE(19.9=100)
C2:
PF0226314=GBP=FE(70.0=100),PF039618=DUF342=FE(51.5=100),PF129382=M_domain=PU(77.1=90.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCCATTTATGCCATAGTGCC
R:
ATCAGCTTGCTGCAGGTGAAA
Band lengths:
183-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)