HsaEX0013061 @ hg38
Exon Skipping
Gene
ENSG00000135205 | CCDC146
Description
coiled-coil domain containing 146 [Source:HGNC Symbol;Acc:HGNC:29296]
Coordinates
chr7:77167658-77241900:+
Coord C1 exon
chr7:77167658-77167824
Coord A exon
chr7:77236947-77237029
Coord C2 exon
chr7:77241691-77241900
Length
83 bp
Sequences
Splice sites
3' ss Seq
CCTTATGTTCTCTTTGCTAGTTA
3' ss Score
8.1
5' ss Seq
GAGGTATGC
5' ss Score
9.12
Exon sequences
Seq C1 exon
AATCGTGAAAAATGGAAGACAGTAGCACAGACACAGAAAAAGAAGAGGAAGAGGAGAAAGATGAAAAGGATCAAGAGCCCATTTATGCCATAGTGCCCACAATTAACATTCAAGATGAGCGGTTTGTTGATTTATCTGAAACTCCAGCTTTCATTTTTCTGCATGAG
Seq A exon
TTACATGCTATGGGAAAACTTCCTGGAACCAGAATGGCAGCGTTAAAAGCCAAGTATACCTTGCTGCATGACGCCGTGATGAG
Seq C2 exon
CACACAAGAGTCAGAGGTCCAACTGCTACAGAATGCCAAACGTTTCACTGAGCAAATACAACAGCAGCAGTTTCACCTGCAGCAAGCTGATAATTTTCCAGAAGCATTCTCCACGGAGGTCTCCAAAATGAGAGAACAACTTCTCAAGTATCAAAATGAATATAATGCAGTGAAGGAAAGAGAGTTCCATAATCAGTACAGATTAAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135205-'2-10,'2-6,12-10
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.513 A=0.000 C2=0.033
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
ENST00000285871fB11484
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCCATTTATGCCATAGTGCC
R:
ATCAGCTTGCTGCAGGTGAAA
Band lengths:
183-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development