HsaEX0013062 @ hg19
Exon Skipping
Gene
ENSG00000135205 | CCDC146
Description
coiled-coil domain containing 146 [Source:HGNC Symbol;Acc:29296]
Coordinates
chr7:76866264-76883884:+
Coord C1 exon
chr7:76866264-76866346
Coord A exon
chr7:76871008-76871217
Coord C2 exon
chr7:76883823-76883884
Length
210 bp
Sequences
Splice sites
3' ss Seq
CTGTTTTTCATGTAACCCAGCAC
3' ss Score
4.05
5' ss Seq
TAGGTAAGT
5' ss Score
9.66
Exon sequences
Seq C1 exon
TTACATGCTATGGGAAAACTTCCTGGAACCAGAATGGCAGCGTTAAAAGCCAAGTATACCTTGCTGCATGACGCCGTGATGAG
Seq A exon
CACACAAGAGTCAGAGGTCCAACTGCTACAGAATGCCAAACGTTTCACTGAGCAAATACAACAGCAGCAGTTTCACCTGCAGCAAGCTGATAATTTTCCAGAAGCATTCTCCACGGAGGTCTCCAAAATGAGAGAACAACTTCTCAAGTATCAAAATGAATATAATGCAGTGAAGGAAAGAGAGTTCCATAATCAGTACAGATTAAATAG
Seq C2 exon
CTTAAAGGAAGAAAAAATCATCATAGTAAAAGAATTTGAGAAGATAACAAAGCCAGGAGTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135205-'6-9,'6-7,7-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.021 C2=0.000
Domain overlap (PFAM):
C1:
PF0226314=GBP=PU(14.0=50.0),PF039618=DUF342=FE(19.9=100)
A:
PF0226314=GBP=FE(70.0=100),PF039618=DUF342=FE(51.5=100),PF129382=M_domain=PU(77.1=90.1)
C2:
PF0226314=GBP=PD(15.0=68.2),PF039618=DUF342=PD(12.5=77.3),PF129382=M_domain=PD(21.7=81.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAAACTTCCTGGAACCAGAATGG
R:
TTACTCCTGGCTTTGTTATCTTCTCA
Band lengths:
132-342
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)