HsaINT0031545 @ hg38
Intron Retention
Gene
ENSG00000101224 | CDC25B
Description
cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]
Coordinates
chr20:3801924-3802376:+
Coord C1 exon
chr20:3801924-3802100
Coord A exon
chr20:3802101-3802280
Coord C2 exon
chr20:3802281-3802376
Length
180 bp
Sequences
Splice sites
5' ss Seq
CCTGTGAGT
5' ss Score
7.21
3' ss Seq
CCATCTGACTCACTTTCCAGAAA
3' ss Score
9.05
Exon sequences
Seq C1 exon
GACCTCGTCATGTACAGCAAGTGCCAGCGGCTCTTCCGCTCTCCGTCCATGCCCTGCAGCGTGATCCGGCCCATCCTCAAGAGGCTGGAGCGGCCCCAGGACAGGGACACGCCCGTGCAGAATAAGCGGAGGCGGAGCGTGACCCCTCCTGAGGAGCAGCAGGAGGCTGAGGAACCT
Seq A exon
GTGAGTGCCTTCCTCCTGGGGTTCACTTTGGCATGCACCTGGGCAGCCACCCCCTTGGCTAAGTTTGTGGCAGAGGGCAGGTGGCAGCCTGGGCATGGCAGAGAAAGGGGGTACCAGCCAGCCAGAGCACTGGGGGGCAGCCCCACCCTGACCCTGGCCTCCATCTGACTCACTTTCCAG
Seq C2 exon
AAAGCCCGCGTCCTCCGCTCAAAATCACTGTGTCACGATGAGATCGAGAACCTCCTGGACAGTGACCACCGAGAGCTGATTGGAGATTACTCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101224:ENST00000344256:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.528 A=NA C2=0.125
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=PD(1.7=5.1),PF066178=M-inducer_phosp=FE(73.4=100)
A:
NA
C2:
PF066178=M-inducer_phosp=PD(21.5=53.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGTCATGTACAGCAAGTGCC
R:
CAATCAGCTCTCGGTGGTCAC
Band lengths:
255-435
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development