HsaINT0033794 @ hg19
Intron Retention
Gene
ENSG00000135837 | CEP350
Description
centrosomal protein 350kDa [Source:HGNC Symbol;Acc:24238]
Coordinates
chr1:180010797-180012327:+
Coord C1 exon
chr1:180010797-180010937
Coord A exon
chr1:180010938-180012190
Coord C2 exon
chr1:180012191-180012327
Length
1253 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGT
5' ss Score
9.65
3' ss Seq
TTGTGTGTGTTCATGTTTAGATG
3' ss Score
8.71
Exon sequences
Seq C1 exon
GTCCATGCAGAATCATTACAGCAGGTGGTTCAATCACAACGGGAAGTAACTGAAGTCCTGCAGGAAGCAACGTGTAAAATAGCAGCTCAGCAGTCAGAAACTGCTCGCCTCACCACAGACGCAGCACGTCAAATCTGTGAG
Seq A exon
GTAGGTGCCACTGAGAACACTTCTCTTTTTACTTCTTTTTAGTCAATCTGAGTAACTTTGATCTTCAGTAATGGGTTTCTAATATCTTAGTAAATGCATACTTTGAATTAGTGACTTTTAGTGGGGGCCATACCCTATTGAAATAAGAGGCACCATTGATTGGAGTGTGTTGTACATGTGATTGAATGTTATAGAGGCAGAAAAAAGATGAAGAGCTCTAAATTTCTGCCCTCTGGTAAGCTTTTTAGAAAAATATCAACTTTATTGATGTATAATTTATAAACAATAAAATGTACCTATTTTAAGTATGCAATTTGGTGAGTTTTCTCTCACACACACACACACACACACACACACACACACACATCTCCCTATAACCATCACCACAATCCAGAAATAGCATATTTCCTCATGTCTCTTTGCAACCAGTCCCTAATCTCAGTCCTGGGGAACCACTGATCTGCTTTGGGTGAAGATGTTTCATTTTTACCCAGAATGATATTAGTTACTGTCTTTTCTTCTATAACGTGGGTATAGCCCAAAGTAGTTTTATTGCTGTCTCTACATAGGATATCACAATTCATAATTGATACAGTTTCACTTTATTTTAGCAGTTATAATTTTTTTAAACCAAAAGTTAGTACTATTTGTAAAATGACTTAGTTATTGGAAATCCATGAATGTACTATATGTTGGGTACTGTGGAGTTGTACATTTTAGTATAAAACTGAGTCTCCTTTCTCAAGAAAATTAAAATGTAGACAACATCAACAAAGATTTCAAAACACTTTAAGTCATTAGTAAAAGGAATAGCTCAAAGTAGTGCTTGAACAAATACTGAATGGATGGTACATGCAGCACTTGCAGTAGTGGTTAAGAATAGGGAAAATGTACTTGACCTGTTGGTCAGCAAAGAGTTAGAAAAGAAGTAGTAATTAAATTGATTCTTGAAGGAAGATTTAATTTTTGGCTTATTACTGCTTATGTTATGCTTTAAGGTTTTCTGTCTAATTCATAGATTGTTATAGCTGGGTGAAACCGTAGAAATCATGTAGTCTAACTCTGTTTTTATAAGATGAAGCTGTTGAGACTTAAAGAGGCTAAATGACTTGTCCACAGTATTTCATCTATTAGTGGCAGAATTTGCTTGTTCTCAAGTCAGTGATCTTTCTTTCCAAGACACTATGCTCCTTCTCAGTTCTCTGACCTTACGTTTTAATACATTTGCCTTTCTTGTGTGTGTTCATGTTTAG
Seq C2 exon
ATGGCAGAGTTGACTAGAACTCATATCTCAGATGCTGTCGTGGCTTCAGGAGCTCCCCTTGCAATACTGTATGACCACCAACGGCAGCACCTTCCAGACTTTGTGAAACAGCTGAGGACCAGAACTGAAACAGATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135837-CEP350:NM_014810:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.257 A=NA C2=0.463
Domain overlap (PFAM):
C1:
PF055966=Taeniidae_ag=WD(100=70.2),PF094945=Slx4=PU(76.7=70.2)
A:
NA
C2:
PF095115=RNA_lig_T4_1=FE(31.5=100),PF0206410=MAS20=PU(54.4=80.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCATGCAGAATCATTACAGCA
R:
CTATCTGTTTCAGTTCTGGTCCTCA
Band lengths:
278-1531
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)