HsaINT0033808 @ hg19
Intron Retention
Gene
ENSG00000135837 | CEP350
Description
centrosomal protein 350kDa [Source:HGNC Symbol;Acc:24238]
Coordinates
chr1:180053153-180056852:+
Coord C1 exon
chr1:180053153-180053313
Coord A exon
chr1:180053314-180056712
Coord C2 exon
chr1:180056713-180056852
Length
3399 bp
Sequences
Splice sites
5' ss Seq
GAGGTTAGA
5' ss Score
4.15
3' ss Seq
TCTGGTTTTTCTAAACTTAGTCA
3' ss Score
3.61
Exon sequences
Seq C1 exon
AAACTACATCTGACCAGAGTGATATTGAAGGTAGGATCAGAGCTCTGAAGGATGAGTTGCGGAAAAGAAAATCAGTTGTGAACCAGCTGAAGAAGGAACAGAAAAAAAGGCAAAAGGAAAGACTGAAAGCCCAAGAAGCCAGTCTGATCAAGCAGTTAGAG
Seq A exon
GTTAGACATAGGAAGAAGGGGGTTTAGTATCAAGGCTAATGTGTATGTGACGTCTAAAATGTTTTTAATGTTGTTAATAAAGTAATGGATTAGGATTCTTCATTATTAGTGTGGTGCCACATTTTATTCTCTTAAAAAAAATCTGAGGGTATCCAAGGACATTCTTGCTTAAAACATTAAATTTTATTTTATTTATTTATTTTTGAGATGGAATCTCGCTCTGTCGCCTAGGCTGGAGTGCAGTGGCGCGATCTCTGCTCACTGCAAGATCCGCCCCCTGGGTTCACGCCATTCTCCTGCCTCAGCCCCCTGAGTAGCTGGGACTACAGGCGTCCGCCACTACGCCCGGCTAATTTTTTGTATATTTAGTAGAGACAGTGTTTCACTGTGTTAGCGAGGATGGTCTCGATCTCCTGACCTCGTGATCCCCCTGCCTCGGCCTCCCAAAGTGCTAGGATTACAGGTGTGAGCCACTGCGCCCAGCCAAAACATTAAATTTTAAATTTAAATATTAAAATAACAAGTATTAAATATTAAAATTGGCTACATATAGTGGTGTGTTCCTGAAGTCCCAGATACTCAGGAGGCTGAGGCAGAATTGCTTGAAGCCAGGAGTTTGAGGCTGTAGTGCACCATGATTGCACCTGTGAATAGCCACTGCATTCCAGCCTGGGCAACATAGCAAGACCTCCACCTCTAAAAAATAAATATTAAAATAAAGTATTAGATTTTTTTTTTCTAAATAAGAAAGATTAGGCCTTTGAAAGAAAGATTGGTGTCTATACCCTTGTAAGCAGAGAAGTATTAGATAAATAATTTTAGCTTTTGGAATTGTTGCTGCTTCCCTTCCCCCTTTCCTCTTTCCTCTTCCTTCCCTCTTCCCTGTCCCCTTTTTTTCTCCTTTTCTTTCCTCCTTCCCCTTCCCCTTTCCCCTTTCCCTTTCCCTTCCCCTTTCCCCTTCCCTTCCCTTATTTCACAGAATGGTGTTTCATGCCACACAACCTATTAAATAGTACACTTCTTTGTGCTATTTGAATAGCTTCTAATTGATAACTCTTAACTTGAATTTTCCCCCAAGCCGTAGCAGCCTTTCTGAGTCTGTCCCAGGCTGGGAACCTGATTTTGATGTCTTCCTTATTCTGTTCTTTCCTGTCCAATTCAGTCACTAGTTCTCATGGATTCTTCTATAAAGTTTCTTGTTTGTCCCTTTCCATTCCTACTGCTTCCAGGCTAGCTGGGGCCCTTATGACCTCTTGCCTCTACTGTCTGCGTAGTCTCTTAGATGTTCTGCCTCATACTGCTTTTCTATTACACACATTCTGCTTCTCTGTTACACACATTCTGTTTCTCTATTACACACATTCTGCCAGCCCGGTGTTCCTAGAACAGGACATTCATTGTAGAATCAGATTGAATCTCCTACTCATTGCAAGAATCCCTTCTCATCTCATCACCAGAGAACATCATTCAACTTCTACCTGAACACTTCCAGTAATAGGAATTTTCAAAATTTCAAGCTAATTGGTTTCCTTGTTAGACTCTAAGTGCTCTAAGTATTAGAAGAGCTCTTTGTTGTATTTAGCCAAAATTTCTGTCCTTTTAATTTCCACCCATTGGTCCTTGTTGTGTAACAGCAAACACATGCTTCTCCTACTGTTATTAATTTAATCATCAAATATTCAAATGCCTATTTATGTGCCAGGAGCTCAGCTAATTACACATATTTTTCATTTAATCCTCACAACAAGGTGTGAGTATTATTATCCCTGTTTTATAGATAAGGAAACTGAGTTTCAGTGAGATTAATGATTTATCCAAGGATACAGAGCTCATAAATGGTGAAACTAGGATTTTAATCTAGCTCTAATTTTAAATTCTGTGGCTTTACCATTGTATTGTCTTCCACACAGAAAATAGGCCTGTTAATAGATCTGGAGAAAATAAACATTTAAACAGGTACACAATACAGAGATGGAATAGGGATTGTAACTTGCACAATGGTTAGAGTAGGAAAAGTGATTAAGATACAATGACCATACTGAGGAGTTCATGCTGGAAAGAAGTGGAAACAAAATTTAAAAATACAGATTATATTCAGGACCGTAGAAGTCAAACTGATGAGTTTGGATTTCATCTTATACGTCAACTAATGAGGAGTCATTGAAATAACTGTTGGAGATAAAGTACTATTAGAATGAATAGTATTGCTCAAAAATGTACCTTAATAGCTATGTCAGTCAGAAAAGAGCCCTCTAGAGAGTGCCATACGATCCATCTCTTCCAGCATTCTACTTAATGGCATAAACAAAGACAAAAGAAAATTCTGTATTTAACTTTTAAAATTACAGTATATGAGATATGCATATATATATATATATATATAAAATACATAGCAGTTCATATAAAAATCTATTGGATTTTATTTGATCACAGATTTAATAAATGGACTGCACTCATATATGTATAGCTTTCAGATCTTAGTAGTCATAGTCCTCATATATACCTATTGAGCTAGAACACCTAGCTGTGGTGTAGGTTTAATACCAGGAGTTATTTTAACAAAAAATGTTGACAATTCAGACGAAGGTAACATGGATGATGAGAGTTGTAAAACAGTGATTTCAGTCCAGATTTTAGGGAACCGTAGCAGTTGACAAGCATCCATCCATCCATTAGTTCATTTTATAAATATTTATTGATAGGCTACTTTGGACCAGGCATTGTGAATAGGACATTGCGTACCAGACATACAGTGTTGAACAAAACACTAGTCTGAAATAGTGAGAGCTGTAAAAGTAAGGACTTCAGCCCAGAAAACTAAGGAATGATATATTAAATGGAGGAATCCCCTTATATTTCATACAAATTATAAATTAGTAAAGTTTTGTTTACAGAATGGGTAATAACCAGGAAACTTTTTTTTTGTAATTCTCAACTATCATACTGTCAACTATATCTTTCTCTTTTCATAATTTGTATCCCTAAGTACTTAGCCCATAAGAAACTTACTGCTATTGAAACTCAGAACAGAATGACTAACTTCTTAAAGATACCATGAAAGTAATAGTACACTCTTTAGAGAATACAAAGAAGTTTTTTAATGTGGCAAGGTATGAATTATTGCTTCATAGTATTAAACTTCTGTAGATTCGCAATGTCATTTCTTAATTGATACTGGAATTACAATTATATATCTTGCTTATATATAGATTATTTTGAGAAGGATGTACAAATAACTATAGAGTTCTGGAGAATGATGCTGAGGGGGGCAGGGAGGGAGATTTTTATATTACATCTTCTTTACTGTTTGAGCATTTTACCTTAAAATATACTATTTTATAATTTAAAATAAGTTTTAAAAATTCTGCCTAGTGACTCCTCTGGTTTTTCTAAACTTAG
Seq C2 exon
TCATATGATGAATTTATTAAGAAAACTGAAGCCGAGCTTAGCCAAGATTTGGAAACATCACCAACAGCCAAGCCTCAGATTAAAACGCTCTCCTCAGCTTCTGAAAAACCCAAGATCAAACCCCTCACACCACTACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135837-CEP350:NM_014810:31
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.888 A=NA C2=0.784
Domain overlap (PFAM):
C1:
PF053946=AvrB_AvrC=PD(57.0=90.5),PF093675=CpeS=PD(50.0=71.4),PF048597=DUF641=PD(73.2=95.2),PF066578=Cep57_MT_bd=PD(89.2=92.1),PF134761=AAA_23=PD(56.2=85.7)
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)