HsaINT0035522 @ hg38
Intron Retention
Gene
ENSG00000122966 | CIT
Description
citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]
Coordinates
chr12:119776358-119776842:-
Coord C1 exon
chr12:119776672-119776842
Coord A exon
chr12:119776409-119776671
Coord C2 exon
chr12:119776358-119776408
Length
263 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGTC
5' ss Score
5.64
3' ss Seq
TTGTGTCTTTTTAATTACAGGCT
3' ss Score
8.28
Exon sequences
Seq C1 exon
GAGTACCAGGCTCAAGTGGAAGAAATGAGGTTGATGATGAATCAGTTGGAAGAGGATCTTGTCTCAGCAAGAAGACGGAGTGATCTCTACGAATCTGAGCTGAGAGAGTCTCGGCTTGCTGCTGAAGAATTCAAGCGGAAAGCGACAGAATGTCAGCATAAACTGTTGAAG
Seq A exon
GTAGTCAGCCACCCTCCAGGAGGGTGCTTTTTGGGTAAAATTGTACATGATCTTAGCAAGAAAAAGGAGAACCTAGTTTAATGAGAAACAACCTAGTTTGAGAAATAGTAGGATACCTTGGAAAACTCTTGGTCTTTATTTACAGAAGATAACATTATTCTTATTTACTATTATTATCTTGGTCACAGAGACCAAGAAAGTAGTCTACACGACTTTTTTAGGTTGTTGAGATTTCCCAATATGTTGTGTCTTTTTAATTACAG
Seq C2 exon
GCTAAGGATCAAGGGAAGCCTGAAGTGGGAGAATATGCGAAACTGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966:ENST00000261833:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.161 A=NA C2=0.802
Domain overlap (PFAM):
C1:
PF0026115=Tropomyosin=PU(7.8=24.6)
A:
NA
C2:
PF0026115=Tropomyosin=FE(8.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTACCAGGCTCAAGTGGAA
R:
TCTCCAGTTTCGCATATTCTCCC
Band lengths:
220-483
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development