HsaINT0041366 @ hg19
Intron Retention
Gene
ENSG00000005339 | CREBBP
Description
CREB binding protein [Source:HGNC Symbol;Acc:2348]
Coordinates
chr16:3832685-3842095:-
Coord C1 exon
chr16:3841982-3842095
Coord A exon
chr16:3832928-3841981
Coord C2 exon
chr16:3832685-3832927
Length
9054 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
3' ss Seq
CTGTCTGTTTGTCGTTATAGCCA
3' ss Score
8.76
Exon sequences
Seq C1 exon
TTGCCCATTGTGCATCTTCACGACAAATCATCTCTCATTGGAAGAACTGCACACGACATGACTGTCCTGTTTGCCTCCCTTTGAAAAATGCCAGTGACAAGCGAAACCAACAAA
Seq A exon
GTAAGTGAGCACGGGGGCAGAGAAGCTTGGAGATGAGAATAGAAGTTGTTTCTAAAGAAAATTCAGAGAGTAGGTAGGGAGTGGGCAGGGGTTATGAGCCATGGAGTGCAGGGTGAGGTAGGGCGGACAGCAGCCCAAGGTACAGCCAAGCTCAGAGGGCAGGCGGGCTCTCCGTGTCAGGAACGGCTGTGATAATGTTGGACCCTGACTCACTCACTGCCTCTCCCTCTCCCTGCCCCCTGCATACATGCACTTGAAGCAGCATGGAACAGCAGAGTCACTTTGTTCACTGAGCCAACACGAAGACATGGTATTTCCTGACAGTTACTCCATACGTGAGAATTTAAATTCCATGTCGCTATAATGGCAGTGACGTCTTAGGGAGGGGGATAGAGGGGATACTTCTTTTGGAATTGGAAAGCCCTTATCCTGAAGTAAATTTTGAAGGCTCTGTCAGTCAGTCTGGGTCAGTATAAAATCCCACACAGACATTTATGAAGGTTTCCCTCTACGTGGAGCTATGGTCCCCAGAACTCTTTGTATAACTAAACGTTCACTCTGCTTCACAGTGAGAGCCTCTGCCCTAGGGCTGCTGCATCCTGATCACCCCAGTCGTTTTGCCGTTGTCTAGGTTGTCTGTAGCCCTCGGCACGGCTGGTTACGCAGCGATCCCTGCTTGTTGGGAGGTCCGCCTGGGGCTCTGGGGCTCCCTGCCATTTGTAGGCTTCAGGCAGTAAGAAGGATGAACCTCCCTCCCGTTTTTCAACCATCTTCCTGTCATTTTAGAGGTAAAACTGTGGTCTTTGGGTGTGTCATTCAGTTTCGGACAGCTAGGAAGTGCCCTTCAGTCTCCTGTCCCCTCTGGCTGGAGCTGTACCCTTAGCGACCCTTCCAGCACAGCACAGTCTTCCTCATCTTCCTCCATCTCGTCTGTGCCATCTTGCCACCCTCCCCTGTTTTGTGTATTACGTGTTCATTCCTCTCATTCTTCTTGATCATCCTTCCTCAAGACCCCGCAGCTGCCTGGAGAACATGTGCTGCTTTTCTTTCTGGTTGTTTCTGAGTGGCCCAGGGAAAGATGGAAAAAGTGCTTTGTTCCTAAGAGTACTGTGGAGTGGCGTGCCAGTGACAGCCCCCGTGGTTTTCCTTTTACTGAGTCCAGCCCACCTCCCTCTGGCGGCGAGGGAGTAGGCAGCGAGCTGACGCTGACCCTGCTTCCTTTAAAGCAGGGTGTCCCTGTCATAGAGAAGAGAAATGCCAGGGTAATGGGGCCTGTTATCTGCCTCCCTACAGAAGAACCACAACGAGTTTCCTTTAAAAGCCAGTTTCCTGGCCAGGCGCAATGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGTTGGGAGTTGGAGACCAGTCTCTACTAAAAACACAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTAATTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTAAACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCAGTGCACTCCAGCCTGGGCAACAAGGGCGAAACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGCCAGTTTCCTAAAAGTCAGTTAAATTATTCTTTGATTGACTAAAATTTGAATTAATAAACAATTTCCCTGGACATTTCTTATATAAAGTGACATTCTGGAATCCTGGGTCTTCTAGAACCAGATATTTGGGACAGTAGTTCTAATGGAATACAGTCTGTTTTTCCTCCCACATTACTGTAAAAGTTTTTTCTTTAGTATATTGTGATGGCTAAATTTCTTGTGTTTTAGGGCACATTTCAGTAATAGGCTCTTTAAGTGCCAAAATATTCATTGTCAAGTTTGTAGTTATACAATATTCTATGAATAATGAGCTAGAATTTTATTCTTAACTTTAATTTGGGGGTGTGGCTTTTTGAGGATCTTTTGTTTTTAGTACATACTACCATGACAGTTGTAAACTTTGGTGATTTCTCTTTTTAAGAAACACTTATGTGGTTTTTGTTTTAAAAGAAAAAAGAAGCGTATGTGGTTTTTTTTTTTTAAACCATCCTTATAACGGCCTGAGTGTTGTGAAAATTGATTCTGTGCATGCTCTCTCAAGTGGTAAACCACAGGTTTTCTACTAGTCAGAATGTAAGATATTACCAGGATGATTTTATAAAGTCACAAGGAAGATTTAGATTAACTTGCTGCAAGGTTTTGGTAGTTTTTTTTTACAAAAGTATGATTGACAAGGTTTCAGCAATATCCTTTTTGTAAATTTTATTGTTTTTTCTCTTCTCCCAAAGCAAATTATGCTTATCGTGTGTGAACTCTTGAGTTAGGAACCCAGAGAGGAAAATGTGAATCTGACCCTACGTTGGCTTAAGGTTGGGTTTTGAAGACAATATATATGTTAAAAATAACGTAAGGGTGACCTCCCTCAAAGGACCGAGGTAGAGACAAGTCAGTGCAATCAGCATTCTTTTCGAGGAGAATTGGAGCGCACCTGACTACTTTGTAGAGAAAGGTGGGACTTGGTGGAGCCCAGTGCAAACAGAATAACAAAGGAAGAACATTTCAGACAGTGGGGACAGTGTCTGCACAGTGCACAGCTTGTGAGGGCATGCATTTGACTGGACTGGGGTTCCTGTGCAAACGAGGTGAACAGAAAGGTGGACTGTGATGAGCTCCTGGAAGCCTCAGGGACTCTGCCGAGACCCACCTGTGCTCGCTCTGTGGAGACTGCCTTAGGGGCCCCGGGACTCTGCTTTTTAGGCAGTGTTTCCCACAGGCCAGCGCTGGTCTTACCTGATGCACACTTCCTTGGTCAGCACATGCTCCACTCTCTTAACTTCTGTGATTAATGTCTCTACTGAGAGAACCTTCCAGAATCACCTGTGGCGCTAATCTGAGGTTCTTTGAAATGAAGCCCAGACCATTGATTACCTTTTTGGCCTGTGTTGAGTTTTGTTTGGTTGGTTGGTTTGTTTTGAGACGGAGTCTTGCTCTGTCACCCAGACTGGCATGCAGTGGCATAGCCAAGTCTCACTGCAGCCTCAACCTCTCGGGCTCAAGCAGTCATTCCACTTCAGCCTCCTGAGTACCTGGGACTGCAGGCATCTGCCACCATACCTGGCTAATTTTTGTATTTTTTGTAGAGATGGGGTTTCACCATGTTGCTCAGGCTTGTCTCGAACTCCTGAGCTCAAGTGATCTTCCCACCTTGACCTCCCAAAAGTCCTGGGATTAGAGGCGTGAGCCACCGCGCCTGGCCTCATTCGATTTTTCCTTGAATTGTTTTTTAAAGATTCTGTAATCACTGATCTCGAGTTAACCATCCCTTATAGCAATATTCAATTTTTTTTGAATAATTAGGACTTGCCAAGATAAGTATCTTATGTCAGTCCTGGCATCTGACCTCCAGTAAATTCAGTGCACAGAGTGGCATGGTTGACTGGGCTTTGGGACCCGTGAGCAGGTTCCCCTCTTGGGGCTTATGCTGCCTCACTTGTGAAGTTCTTGCTGCTCAAAGTGTAGGCCTCAGGGAAGCCATAGAGGTGCTCCCAGGTTGTAAGCAATAAAGAAATTGGGCCCCCATTTGAGACCTCTTATATTAAAACCTGCATTTTTATAAAAATCCTGGGTGATTAGTGTGCACATTAAAATCTGAGATGCACTGCTCTGGATGCCTTGGAAGACCAGGTATCTGGGCCAGTGCTGGTGAGAGGGTTTGAGTCATTCTCTGAGAGAGAGACCAGGGGTTTTCCAACCTAGAGTCCCCCAGGGACTGTTGAAGCAAGTGTGCAGGGTCGGCCCCAGAGCCAGCCTAATGCACGCACTGTCCCGGCTGCGTCAGCCATGGCCCCAGCTGCTGCCCGGCATCTCCATGAGTGTAGCTCCCACTGCTTCACCTGGCAACATGTTCCATCTGTAGGTGCCTCAGATTGTTTAAAACACCTCCTTTTGGCCGGACGCAGTGGCTAACGTCTGTAATCCTTGCACTTTGGGAGGCTGAGTGAGACAGGCGGGTTGCCTGAGCTCATGTTCAACACCAGCCTGAGCAACACAGTGAAACCCCGTCTCTACTAAAATACAAATAATTAGCTGGGCATGGCAGCATGCGCCTGTAGTCCCAGCTACTCGGTATCCTGAGGTGGGAGGCTGAGGCAGGAGAATGACTTGATGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTACGTCTCAAACAAAACAAAACAAAACAAAAAACCAAAACAAAACAAAAAAAAAAACCTCCTTTTTTTATATGGAGTCAAGATCTCCGTCCTTTGAACTGCCACTCATCGAATAGCCCATCAGGTGCCCAGTGAGTGTGTGTGGAGCAGGCCCTTTGTTCACTTGAGGGCCCTTCAGAGATTTTCACCTCTTTTGACAGACTGTAGTGGGATGGGGGACAGCAAGGAGCAGAATCTGAAGGCTGTAGAGAGAATGGTGGGCTTGATTGACCCTGACTTAAGCACCAAAGGGTCGTGGGTGATGTGTTTCATCTGAACAGCTTTTCTCCTTGCTAGCAAGGAGCAGTGTCACTGCGCCAGTGTCACTTGGCTTCTGAAGAAAGCCTTTTGCTTGAGGGCTTGTGGCCGTGCCTGATAGGAGGCTGAGTCTCCAGCCTGGCAGTGCCTGGGTTCCCCTCAGTGCTTCTCTTCACTGTGGTGCCCCACGCAGTGCATAGGAAGGTGCCAGGTAGGAAGTAGGTCCTGGCCCACACAATGCCCGCAAGGTACGGTGGTGCCACCAGCAACTTTGTAGAGATGGCTGCAGGTCTGAATAAATTCTTTTTTTTTTTTTTTTGAGACGAAGTCTCACTCTGTCGCCCAGGCTAGAGTGCAGTGGCGCGATCTTAGTTCACCGCAACCTCCGTCTCCCTAGTTCAAGTGATTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACATGCCACCATGCCTGGCTACTTTATGTATTTTTAGCAGAGATGGGGTTTCACCATGTTGTCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTCCCCACCCTCATACTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCTGAATAAATTCTAGCATTGCTTTTTTAGTAGAAATCTAAGTGTCTTGGTATCCTTGGGAATTTGGTTCCAGGACACCCCAGGTATACCAAAACCAGGTGGACTCAAGCCCTACAGCTGGCCTTCCCCATACACAAGTTTCGCCTCCCGCAAGCACTGTGTTTCTGGCCTGCGTTGGGTGACCCCGTGGCTCACTCTCGTGCTGGTGAAGCATCAGCTGTAGCAACTACTGCTCTGCTTCATGGTCTGTCTCCCCCTACCCTCACAAAGTTTGGAGATTTGATTCATGTCCGTTTTCACTGAATTTCCAAATGGAGTTCAGTTTTATTGAGGATGATTAGGGGCTTAAGTTGTCTGAGTAACTGAGTTCTTTGCATCAGCAACATAGACTGTACAGAAAACCTCTTAGTGGAACATTCCTTTTTTCTTTTGTTTTTTGAGACAGAGTCTCTCTGTTGCCCAGGCTGGAGTGTAGTGGCGCGATCTCAGCTCACTGCAACTTCTACCTCCTAGGTTCAAGCGGTTCTCCTGCCTCAGCCTCCCAAGTAGCTGAGATGACAGGCACGCACCACCACACTCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTATTAGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCAGTTACACTTGGCCGTACCCGGCCTCTTAGTGGAACATTGTTTGTGCATGAAGAGTGGCAGGTGAGTCCGAGAAAGAGCCTGCTATAAAACTTGGCCTTTTGTTCATAGGTCATAGGCTCCTTCTTCAGCAACATCAGAAGGGGTGGTGAGACTAGGGGATGTTGGGGAGCTTTAAAGAGGTAAATATCCGGGACAGGAGTGTTGCCTGATGGGCCCAGAAGAACCCAGCCACTGTGTTAGTGCATTGCAGGTGTGTTGTGACTTCCTAAAAGTTAGAGCTTTATGCTCTAGCGAGGAAAAAAGATGTAAAAATGGCCAAATGAGCACACGGCCTTGACATTGGAAGAAGTTAAGTGGCAATAATACAGAAAGGATAAATAGAGAAACTTCATCCTTAGGGATGCCAGGTAGATGGACCAATCTCCGTGCATTTCTGTTCAGTTCCAAGACACTCCATGGGCTGCGCTGCGAGGGCCCACGATGTGCTGGCCGCTGCGCTATAGCTGGCACGTCCCCTGGACTCTGCACAGCAGGTTACGTGGCCCATGTGGCAGGTGGTGAAGAGCAAAACCGAATTTGACATTAATCCCACCTTTCAGGGATGCACAGGGAACGTGACATGAGCCTGATTTTCCCTGTCCCAGGGTTCCAAGGTGCAGTTTGGGTGCATTAGGTGATTATTAGATAATCTGTTGTCCCTAGGCTCAGGGAATGCAGAGATTGTGCCCACACCATGTCTGGGAGCCTGGCAGAGTGTACTCACTGAGTCTGTCACGTGAGTGAGTGAATACACGAAGGGTCAGTGTCTAAAGACAAGCGGGTACAGGAGTCACTGTGGGATTTCAGAGAGGGATTGGGAATACCACCATGGAGCACTTGGAGCACCTTGAGGTTGCAGTACAGTTGATGGTGGCTTATACATAGTGACTCCCCTTTCAGTCAGCCATCACCCTGCAGTGAATGCCTGAGCACCCTTACCCTTCAGTATTTGTGTCATTTCATGTAATAGCATCATTTGGACTTCAAATTCAGCCATGCTTAAATGGCAGAGACCTTCTTTATTTGTTCATAATTAATTTCCTTTGCTTCTGAATTTTAGAAATGATGAGTTCCAAATGCTTCTCATAGGTATATTTTCTTTTAAAATAAAAATATAATAATGTTTACGTTTAGAAAATGAATGCCTCTAACACAAAATGCAGTGACCGTGTCAGCAGCTTCCGTGGGAGGCCTATGTGAGTATGAGGCGTTGGCTGCCCTGTAAGTGCTGTGAGCTTAGGAGTGGCATTCACTGTAAGGTGGGGCATTTTAGTTAAGTAGATGGCACTTGGGGAGGTGTGGATAAAAGAGAAATGTAGTAGGAAGAAGTCAATAAAGGGTTTACGGGAAATGGAAGGCTCCATACTTTGTTTCTTTTAAGTTCTTCTCCACAGTCCATCACCATGTGTGTTAAATATAGTGTAGCCCTGTTCTTCCTTACAGCGCAAGGTTGTAGAAAAATAAACTATCCTACCACTGTTAACTTTGATTTCTATACCATAGTGCTTCTTAAAAATGTAGGATGTCGGTTTCAGAAGTATGGTGGACACATGTTTAAAGTTTTGGGGAGTAGTAAGTATTAGAATACTTTTAAAGGTATTGTGCGTGACTTACTTCAGCTACACACTTGTCATAAAGTGCACCTTGGGAGTTGCTTTTCATTTATGTTAATGAGTGCTTGGTGTATGTAGTTGTGTCTGATGAGTGTTAATGAGTTGATCTGAATATCATTATTAGAAAAGTTAATAGTATGGAAAGTATAATTACCAGGAATTTTTTTTCACACATTTTAGTTTAATTAAGTTGCTCTGGTAGGTATTGGGTTTATTATAGGTGTGCTGATGGTTGAATGTGAGAATATTACTGTTACACATAGTGGTTGGGATTTGAAAGAAAGGCTTTGTGGTCGTGTTTTATGTATCAAAAATGGTGTGTTATAGCAACAACACTATAAGATGCTATTTTTAACATGACTCTAAAATTTGTGGAAGTTAGAAAGGAACTCAAAAATAGGAATAAATGGTATCATATAGAACTTCTGCCATATGATAAATTTTCACACAACAGCATTTGGGTTGTTGCGACAGATGAGGGGGCAGGCAAACAGGTAACAGGTGGGTAGGTAGGTGGGTAGATGAATTGACCTTGAAATGTCCAAGTTGATGCAAGTTTGGAGTTGTCTCTCCATTACCTTGGAAGCCCTTTGGGATGGAGCTCCTTATGTTGACACCAGTTTTTCCTTTAGTCTCCTGGGGTTAGCTAGCTGGATGGGGCAGCTTCCCTGCCAGCCAGCAGTGGGCCTCAGTAGCAGAAGCTGACTTTGGCCACGTGAGGCAGAGCCACCTCCTGAATATCAGAGGTGCTGAGGTAGCCCCTGGATAATAAGACCCATGCAGAATTGCGAAGCCTCACTCCAACCTTAATTTCAAACAGCTCAGTCAGTCAATCAATCAAGTACAGTATTTCTTGAACAGCTTCATGTAGCCGGAGAGCTCAGCATGGTGCTCTGCTGCATAGGAATCCCATCAGAAGGATATGTCCATGCTGTCATTGTTTGTGTATGTTTCAAGGACTTGCAATTATGTGATTTGGAAGAGCACATTATAGATTTATTAATCAAAACTGACCGACCAGGTATCATCTCTGCTCCTTCTCTTAAGCCCTCTGTACCTGTGCAGGTGAGCAGTGAAGGACAGGGTTGGGGTCAACAGGAGGGGGCTCCTCTGTTCATCTCAGAGGTGTCTGCTGGTCCCCAGAGAATCAGACGTTTCCCTTGTCATACATTTGCCACTCCCTGGAACTGACTTCTTGAGGAGTCTCTAGGTTTTAAGACATAATAATTTTTTTCAAGTGTTATCTGTGAGATTTTATGGTCTGTTGCATGCTAAGATAGAAACTTGACTTTTCTTTAACTTTTTGTTCCTCACTTACTGCTAGGCAGAATAAATGAGTCCTTCAGCACAGTTCCTTTCTCCCTAGGCTTGTTTACTGCTTTATGATATTCATGTGTAGTATTTTGATGAAATGTATTTGCTTCTCAATAGTTTTTAAATCATTCGTGGGCTTCTCCCTTTTACTTACCTCTCGTTTTTGTCTGTCTGTCTGTTTGTCGTTATAG
Seq C2 exon
CCATCCTGGGGTCTCCAGCTAGTGGAATTCAAAACACAATTGGTTCTGTTGGCACAGGGCAACAGAATGCCACTTCTTTAAGTAACCCAAATCCCATAGACCCCAGCTCCATGCAGCGAGCCTATGCTGCTCTCGGACTCCCCTACATGAACCAGCCCCAGACGCAGCTGCAGCCTCAGGTTCCTGGCCAGCAACCAGCACAGCCTCAAACCCACCAGCAGATGAGGACTCTCAACCCCCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005339-CREBBP:NM_004380:5
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.179 A=NA C2=0.973
Domain overlap (PFAM):
C1:
PF0213511=zf-TAZ=PD(32.1=66.7)
A:
NA
C2:
PF0213511=zf-TAZ=PD(5.2=3.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)