HsaINT0044294 @ hg38
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]
Coordinates
chr10:133527357-133528640:+
Coord C1 exon
chr10:133527357-133527572
Coord A exon
chr10:133527573-133528480
Coord C2 exon
chr10:133528481-133528640
Length
908 bp
Sequences
Splice sites
5' ss Seq
CGGGTAAGA
5' ss Score
9.84
3' ss Seq
CTAGCCACGGGTCTCCGCAGTTG
3' ss Score
3.59
Exon sequences
Seq C1 exon
GATTGTCTCCCGGGCTGGCAGCAGGGCCCCAGCGGCACCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTGGTGTCCATGTGGAGGCAGGTGCACAGCAGCTGGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAATTGAAGAATATTCCCAAGTCCTTCACCCGG
Seq A exon
GTAAGAGAAATAGTGTTGATTTTAGGGAGAATAACTCAGCAATTGGATCTGGTATGTGTGTATTCAACTCATTTGCAGACAAATTGTGGTTGTTCAATACCAGCCTGTTGTGAATTACCTGAATTGATAGCATCCTGGAGCGACACTCAAAATGTGTCGCCTGTGGTGCAGCTGGAGCCCGGAGCCTGCGTGCCAGGCCCCGGAGGCCCCCGCCGGTGCCTTGTCCTGGGGCTGATGATGGGGAGGCCGGCGAGGCCGGGCTGCTGCGACGCCAGGATAACCGGGCTGGCGGCCAGATGCGCACTCGCTGGGCGTCCGCCTGTGTTTGCCAAAGCACGAGTTGAAACGTGAAGTGTTGGGCCAGCCCGTGTGGCACCAATACCTGCCGCCTACGACTGTTGTGAACACTGAATGGGCCAACAAACCTAAACGTTAAATGAACTGATAACGCCGTCAGCACGGAGCAGGCGCTGGGTGTTTGCGCTCTTGCGCGTGCGCTCTGTGGGGCGCAGGCTGACGGCGGGCGGGGGTCGCCTGCTCCAGCTCGGGCTCCCGCGCCAGAACCGGGTCCAGAACCTTGATTCCGGAAGCGGGCAACGGGGTGGTTGGTGGGCGCGCCTGAGGGAAGGGACGTGAGGAGCCGGAGTCCGCGGAGTTGCCGCGGAGTTGTCCGCGGAGTCCAGGCGGGTGGGGAGCAGAGCAGCTGGAACCCCCCGAGCGCCCTGCAGACGCAGCAGCCTCTTGAGGGGAGGGTCTCCCCCACCTCGGGCTGGACAAAGACAGCTTTTCCCCACGTCCCTCTGGGTTCTCTAGAGCAACAGCAATACCCGCCCGGCAGGGGTGTGGCTTAGAGCCCCGCACCTCCTCGCCGCGCGGCGGGCCTGACTTCTAGCCACGGGTCTCCGCAG
Seq C2 exon
TTGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTGATGCACGGCTACAAGGCGGTGAAGGAAGCGCTGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCACAGGGACAGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649:ENST00000463117:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(10.5=44.1)
A:
NA
C2:
PF0006717=p450=PD(48.1=92.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCGGCACCATGTCTG
R:
GTCCCTGTGCGCATGGAAC
Band lengths:
344-1252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development