HsaINT0044296 @ hg38
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]
Coordinates
chr10:133531585-133532284:+
Coord C1 exon
chr10:133531585-133531734
Coord A exon
chr10:133531735-133532123
Coord C2 exon
chr10:133532124-133532284
Length
389 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCGT
5' ss Score
9.49
3' ss Seq
CCTGACTGCCTGTTTTGTAGGCC
3' ss Score
7.64
Exon sequences
Seq C1 exon
GAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAG
Seq A exon
GTGCGTATCTGCTGCCTAGCAGGGCCCAGTCCTCTTGCAGACCAGCGGTGTGGGGAGCCCTGGCTGGGACTCCTAGACTGCATCTGAACCACAGGGACCTACGGACAAGGAGAGGGTCTCGTGAGTCCCCAGATACTGCATTTTACAACTCTAGGTTCCAGCTACACAGTTCAGGGAGCAAGGGTGGCCATTAAACACGTGACTTGTATCCTAAATACTGTTGAAAAGCAAAGGAAACTCAAACAGGTTCAGACATTCACTATCTTTCGTAAACTGGCAGTTTTCAGGGCACCTTCTCACAGGCCTTGGTGAACCTCAGTGGGTGACTGAGCAGGTGGAGGAGTCTCCTCACCCCCATCTTCTGGTTGCCCTGACTGCCTGTTTTGTAG
Seq C2 exon
GCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649:ENST00000463117:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(10.9=100)
A:
NA
C2:
PF0006717=p450=FE(11.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTAATAATGGACCTACCTGGAAGGAC
R:
CTGGAGCCAGGGAGTGCT
Band lengths:
302-691
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development