HsaEX0018282 @ hg38
Exon Skipping
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]
Coordinates
chr10:133531585-133532868:+
Coord C1 exon
chr10:133531585-133531734
Coord A exon
chr10:133532124-133532284
Coord C2 exon
chr10:133532692-133532868
Length
161 bp
Sequences
Splice sites
3' ss Seq
CCTGACTGCCTGTTTTGTAGGCC
3' ss Score
7.64
5' ss Seq
CAGGTGAAG
5' ss Score
6.66
Exon sequences
Seq C1 exon
GAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAG
Seq A exon
GCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAG
Seq C2 exon
CTTTACAATAATTTTCCCAGCTTTCTACACTACTTGCCTGGAAGCCACAGAAAAGTCATAAAAAATGTGGCTGAAGTAAAAGAGTATGTGTCTGAAAGGGTGAAGGAGCACCATCAATCTCTGGACCCCAACTGTCCCCGGGACCTCACCGACTGCCTGCTCGTGGAAATGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.015 A=0.000 C2=0.014
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(10.9=100)
A:
PF0006717=p450=FE(11.6=100)
C2:
PF0006717=p450=FE(12.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGGAAACAGGGCAATGAGAG
R:
TTCTCCATTTCCACGAGCAGG
Band lengths:
250-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development