HsaEX0018282 @ hg19
Exon Skipping
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450, family 2, subfamily E, polypeptide 1 [Source:HGNC Symbol;Acc:2631]
Coordinates
chr10:135345089-135346245:+
Coord C1 exon
chr10:135345089-135345238
Coord A exon
chr10:135345628-135345788
Coord C2 exon
chr10:135346196-135346245
Length
161 bp
Sequences
Splice sites
3' ss Seq
CCTGACTGCCTGTTTTGTAGGCC
3' ss Score
7.64
5' ss Seq
CAGGTGAAG
5' ss Score
6.66
Exon sequences
Seq C1 exon
GAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAG
Seq A exon
GCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAG
Seq C2 exon
CTTTACAATAATTTTCCCAGCTTTCTACACTACTTGCCTGGAAGCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. Stop)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.029 A=0.148 C2=0.017
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(10.9=100)
A:
PF0006717=p450=FE(11.6=100)
C2:
PF0006717=p450=FE(12.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAATAATGGACCTACCTGGAAGGACA
R:
GGCTTCCAGGCAAGTAGTGTA
Band lengths:
186-347
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)